STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB65709.1Methanophenazine hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (596 aa)    
Predicted Functional Partners:
AKB65710.1
Methanophenazine hydrogenase small subunit precursor.
 
 0.993
AKB65583.1
Methanophenazine hydrogenase small subunit precursor.
 
 0.974
AKB65716.1
Methanophenazine hydrogenase small subunit precursor.
 
 0.974
AKB64111.1
CoB--CoM heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
  
 0.894
AKB64843.1
Coenzyme F420 hydrogenase subunit gamma.
  
 0.881
AKB65713.1
Methanophenazine hydrogenase maturation protease.
 
 0.868
AKB63515.1
CoB--CoM heterodisulfide reductase subunit B.
  
 0.863
AKB63516.1
CoB--CoM heterodisulfide reductase subunit C.
  
 0.863
hypA
[NiFe] hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.843
AKB64109.1
CoB--CoM heterodisulfide reductase subunit B.
  
 0.842
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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