Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rpl2LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (238 aa)    
Predicted Functional Partners:
rps17e
SSU ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family.
  
 0.999
rpl12
LSU ribosomal protein L12a (P1/P2); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family.
   
 0.999
rpl10
LSU ribosomal protein P0 (L10p); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
 
 0.999
rpl1
LSU ribosomal protein L10Ae (L1p); Binds directly to 23S rRNA. Probably involved in E site tRNA release.
 
 0.999
rpl11
LSU ribosomal protein L12e (L11p); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
 
 0.999
spt5
Putative transcription antitermination protein NusG; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
 
 0.999
rpl40e
LSU ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.999
eif5a
Eukaryotic translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
   
 
 0.999
rpl18a
LSU ribosomal protein L18Ae.
  
 0.999
rpl31e
LSU ribosomal protein L31e; Belongs to the ribosomal protein L31e family.
   
 0.999
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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