STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpl2LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (238 aa)    
Predicted Functional Partners:
AKB63202.1
Translation elongation factor 1 alpha-related protein.
  
 0.999
srp54
Signal recognition particle, subunit Ffh SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
 
 0.999
rps17e
SSU ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family.
  
 0.999
AKB63314.1
UDP-glucose 4-epimerase.
 
 0.999
AKB63337.1
dTDP-glucose 4,6-dehydratase.
 
 0.999
AKB63366.1
UDP-glucose 4-epimerase.
  
 0.999
AKB63448.1
GTP-binding protein RBG1/RBG2.
  
 
 0.999
rpl12
LSU ribosomal protein L12a (P1/P2); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family.
   
 0.999
rpl10
LSU ribosomal protein P0 (L10p); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
 
 0.999
rpl1
LSU ribosomal protein L10Ae (L1p); Binds directly to 23S rRNA. Probably involved in E site tRNA release.
 
 0.999
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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