STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (304 aa)    
Predicted Functional Partners:
AKB65812.1
Quinolinate phosphoribosyltransferase (decarboxylating); Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
 
 
 0.998
AKB66288.1
Molybdenum transport system protein ModD; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
 
 
 0.997
AKB65809.1
L-Aspartate dehydrogenase.
    
 0.931
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
    
 0.833
AKB66416.1
Proline 2-methylase for pyrrolysine biosynthesis.
 
  
 0.666
AKB64613.1
Serine O-acetyltransferase.
  
    0.621
AKB64966.1
Serine O-acetyltransferase.
  
    0.621
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
  
  
 0.513
AKB65923.1
Homocysteine desulfhydrase.
  
  
 0.513
AKB63676.1
5-amino-6-(5-phosphoribosylamino)uracil reductase.
 
  
 0.496
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.