STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AKB65827.1Iron-sulfur cluster assembly ATPase protein SufC. (235 aa)    
Predicted Functional Partners:
AKB65828.1
Iron-sulfur cluster assembly protein SufB.
 
 0.999
AKB63409.1
Iron-sulfur cluster assembly protein SufB.
 0.993
AKB66347.1
Cysteine desulfurase.
 
 
 0.927
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
  
 
 0.838
AKB64417.1
Scaffold protein.
  
 
 0.791
AKB65924.1
Scaffold protein.
  
 
 0.791
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
     
 0.649
AKB65826.1
Putative adenosylcobinamide-phosphate guanylyltransferase CobY.
       0.645
AKB65824.1
Putative alpha-ribazole-5'-phosphate phosphatase CobZ.
       0.595
AKB65861.1
Putative iron binding protein from the HesB_IscA_SufA family.
  
 
 0.524
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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