STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB65912.1Malate dehydrogenase; Belongs to the LDH/MDH superfamily. (307 aa)    
Predicted Functional Partners:
AKB66336.1
Citrate synthase (si).
  
 0.998
AKB64817.1
Fumarate hydratase class I, aerobic; L(+)-tartrate dehydratase beta subunit.
  
 
 0.992
AKB64818.1
Fumarate hydratase class I, aerobic; L(+)-tartrate dehydratase alpha subunit.
  
 
 0.992
AKB66050.1
Pyruvate carboxyl transferase subunit B.
    
 0.983
AKB66049.1
Pyruvate carboxyl transferase subunit A.
    
 0.976
ppcA
Phosphoenolpyruvate carboxylase, archaeal; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family.
     
 0.972
AKB65270.1
NAD-dependent malic enzyme.
  
 0.960
AKB63559.1
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
 0.956
AKB64254.1
Aspartate aminotransferase.
  
 0.955
AKB65527.1
Biosynthetic Aromatic amino acid aminotransferase alpha / Aspartate aminotransferase.
  
 0.955
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.