STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB65940.1Hypothetical protein. (110 aa)    
Predicted Functional Partners:
tmk
Thymidylate kinase.
    
  0.841
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
    
  0.818
AKB66122.1
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.680
AKB63275.1
Bifunctional deaminase-reductase domain protein.
    
  0.598
AKB63604.1
Dihydrolipoyl dehydrogenase.
  
 
  0.536
AKB64603.1
Dihydrolipoamide dehydrogenase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 
  0.536
AKB65520.1
Hypothetical protein.
       0.520
corA
Magnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
  
    0.510
thyA
Thymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily.
    
  0.468
pcn
DNA polymerase sliding clamp protein PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
 
 
   0.465
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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