STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB65949.1Signal-transducing histidine kinase. (574 aa)    
Predicted Functional Partners:
AKB64870.1
Response regulator receiver.
 
 0.872
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
  
 0.631
gap
NAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase archaeal.
 
 
 0.608
AKB64475.1
Response regulator receiver.
 
 0.605
AKB65948.1
Methylcobamide:CoM methyltransferase MtaA.
 
   
 0.569
pcn
DNA polymerase sliding clamp protein PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
 
  
 0.561
AKB66530.1
Two-component response regulator.
 
 
 0.508
AKB66336.1
Citrate synthase (si).
 
 0.500
AKB65029.1
Sensory transduction histidine kinase.
 
 
 0.497
AKB63429.1
Two-component response regulator.
 
 
 0.494
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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