STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB66002.1O-phosphoseryl-tRNA:Cysteinyl-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (386 aa)    
Predicted Functional Partners:
sepS
O-phosphoseryl-tRNA(Cys) synthetase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys).
  
 0.999
cysS
Cysteinyl-tRNA synthetase.
     
 0.928
pheS
Phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
   
 0.843
rpoL
DNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
 
     0.583
AKB66296.1
Formylmethanofuran dehydrogenase (molybdenum) subunit D.
  
     0.537
thrS
Threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
   
 0.474
AKB63680.1
Hypothetical protein; Belongs to the UPF0235 family.
  
     0.460
AKB63589.1
Putative methanogenesis marker protein 3; Belongs to the UPF0288 family.
  
    0.446
csl4
Exosome complex RNA-binding protein Csl4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.
 
     0.437
mtd
F420-dependent methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
  
     0.427
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.