Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB66050.1Pyruvate carboxyl transferase subunit B. (573 aa)    
Predicted Functional Partners:
AKB66049.1
Pyruvate carboxyl transferase subunit A.
 
 
 0.999
AKB66517.1
Pyruvate:ferredoxin oxidoreductase, gamma subunit.
  
 
 0.991
AKB66519.1
Pyruvate:ferredoxin oxidoreductase, alpha subunit.
    
 0.991
AKB66520.1
Pyruvate:ferredoxin oxidoreductase, beta subunit.
  
 
 0.991
AKB65912.1
Malate dehydrogenase; Belongs to the LDH/MDH superfamily.
    
 0.990
AKB66518.1
Pyruvate:ferredoxin oxidoreductase, delta subunit.
    
 0.990
AKB64079.1
2-oxoglutarate oxidoreductase, alpha subunit.
    
 0.978
AKB64080.1
2-oxoglutarate oxidoreductase, beta subunit.
  
 
 0.954
ppcA
Phosphoenolpyruvate carboxylase, archaeal; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family.
     
 0.952
AKB65180.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
   
 
 0.947
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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