AKB66089.1 protein (Methanosarcina mazei) - STRING interaction network

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AKB66089.1

Hypothetical protein. (72 aa)

Predicted Functional Partners:

grpE

0.765

dnaK

0.549

AKB66478.1

0.549

hisG

0.467

argB

0.466

hisB

0.466

argD

0.466

Your Current Organism:

Methanosarcina mazei

NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKB66089.1	AKB66478.1	MSMAS_2893	MSMAS_3282	Hypothetical protein.	Chaperone protein.	0.549
AKB66089.1	argB	MSMAS_2893	MSMAS_0092	Hypothetical protein.	Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.	0.466
AKB66089.1	argD	MSMAS_2893	MSMAS_3257	Hypothetical protein.	Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.	0.466
AKB66089.1	dnaK	MSMAS_2893	MSMAS_2196	Hypothetical protein.	Chaperone protein DnaK; Acts as a chaperone.	0.549
AKB66089.1	grpE	MSMAS_2893	MSMAS_2195	Hypothetical protein.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.765
AKB66089.1	hisB	MSMAS_2893	MSMAS_3163	Hypothetical protein.	Imidazoleglycerol-phosphate dehydratase.	0.466
AKB66089.1	hisG	MSMAS_2893	MSMAS_3165	Hypothetical protein.	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.	0.467
AKB66478.1	AKB66089.1	MSMAS_3282	MSMAS_2893	Chaperone protein.	Hypothetical protein.	0.549
AKB66478.1	dnaK	MSMAS_3282	MSMAS_2196	Chaperone protein.	Chaperone protein DnaK; Acts as a chaperone.	0.902
AKB66478.1	grpE	MSMAS_3282	MSMAS_2195	Chaperone protein.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.992
AKB66478.1	hisB	MSMAS_3282	MSMAS_3163	Chaperone protein.	Imidazoleglycerol-phosphate dehydratase.	0.476
AKB66478.1	hisG	MSMAS_3282	MSMAS_3165	Chaperone protein.	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.	0.486
argB	AKB66089.1	MSMAS_0092	MSMAS_2893	Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.	Hypothetical protein.	0.466
argB	argD	MSMAS_0092	MSMAS_3257	Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.	Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.	0.995
argB	grpE	MSMAS_0092	MSMAS_2195	Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.570
argB	hisB	MSMAS_0092	MSMAS_3163	Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.	Imidazoleglycerol-phosphate dehydratase.	0.632
argB	hisG	MSMAS_0092	MSMAS_3165	Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.	0.639
argD	AKB66089.1	MSMAS_3257	MSMAS_2893	Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.	Hypothetical protein.	0.466
argD	argB	MSMAS_3257	MSMAS_0092	Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.	Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.	0.995
argD	grpE	MSMAS_3257	MSMAS_2195	Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.507