| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKB63220.1 | AKB63601.1 | MSMAS_0024 | MSMAS_0405 | FAD/FMN-containing dehydrogenase. | UbiA prenyltransferase family protein. | 0.563 |
| AKB63220.1 | AKB65806.1 | MSMAS_0024 | MSMAS_2610 | FAD/FMN-containing dehydrogenase. | (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.563 |
| AKB63220.1 | fni | MSMAS_0024 | MSMAS_2914 | FAD/FMN-containing dehydrogenase. | Isopentenyl-diphosphate delta-isomerase, FMN-dependent; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.850 |
| AKB63601.1 | AKB63220.1 | MSMAS_0405 | MSMAS_0024 | UbiA prenyltransferase family protein. | FAD/FMN-containing dehydrogenase. | 0.563 |
| AKB63601.1 | AKB65806.1 | MSMAS_0405 | MSMAS_2610 | UbiA prenyltransferase family protein. | (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.777 |
| AKB63601.1 | AKB66108.1 | MSMAS_0405 | MSMAS_2912 | UbiA prenyltransferase family protein. | Geranylfarnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.791 |
| AKB63601.1 | fni | MSMAS_0405 | MSMAS_2914 | UbiA prenyltransferase family protein. | Isopentenyl-diphosphate delta-isomerase, FMN-dependent; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.864 |
| AKB63630.1 | AKB66108.1 | MSMAS_0434 | MSMAS_2912 | Hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. | Geranylfarnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.583 |
| AKB63630.1 | AKB66111.1 | MSMAS_0434 | MSMAS_2915 | Hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. | Isopentenyl phosphate kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. | 0.725 |
| AKB63630.1 | fni | MSMAS_0434 | MSMAS_2914 | Hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. | Isopentenyl-diphosphate delta-isomerase, FMN-dependent; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.806 |
| AKB63630.1 | mvk | MSMAS_0434 | MSMAS_2916 | Hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. | Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.890 |
| AKB64251.1 | AKB66209.1 | MSMAS_1055 | MSMAS_3013 | Serine--glyoxylate aminotransferase. | Rieske 2Fe-2S iron-sulfur protein. | 0.820 |
| AKB64251.1 | fni | MSMAS_1055 | MSMAS_2914 | Serine--glyoxylate aminotransferase. | Isopentenyl-diphosphate delta-isomerase, FMN-dependent; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.883 |
| AKB65806.1 | AKB63220.1 | MSMAS_2610 | MSMAS_0024 | (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | FAD/FMN-containing dehydrogenase. | 0.563 |
| AKB65806.1 | AKB63601.1 | MSMAS_2610 | MSMAS_0405 | (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | UbiA prenyltransferase family protein. | 0.777 |
| AKB65806.1 | AKB66108.1 | MSMAS_2610 | MSMAS_2912 | (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Geranylfarnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.883 |
| AKB65806.1 | fni | MSMAS_2610 | MSMAS_2914 | (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Isopentenyl-diphosphate delta-isomerase, FMN-dependent; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.892 |
| AKB66108.1 | AKB63601.1 | MSMAS_2912 | MSMAS_0405 | Geranylfarnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | UbiA prenyltransferase family protein. | 0.791 |
| AKB66108.1 | AKB63630.1 | MSMAS_2912 | MSMAS_0434 | Geranylfarnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. | 0.583 |
| AKB66108.1 | AKB65806.1 | MSMAS_2912 | MSMAS_2610 | Geranylfarnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. | (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.883 |