Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB66127.1Hypothetical protein. (101 aa)    
Predicted Functional Partners:
AKB66128.1
Fumarylacetoacetate hydrolase family protein.
       0.946
gltX
Glutamyl-tRNA synthetase / Glutamyl-tRNA(Gln) synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
 
     0.800
AKB63393.1
Phosphoserine phosphatase.
  
     0.712
AKB66123.1
Glycerol dehydrogenase.
  
     0.711
AKB64203.1
Replication protein A (two OB fold, one zinc finger).
  
     0.709
AKB65913.1
Hypothetical protein.
  
     0.709
AKB64204.1
Hypothetical protein.
  
     0.697
pyrK
Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
 
     0.672
AKB63219.1
Archaeosine tRNA-ribosyltransferase type 2.
  
     0.667
AKB65271.1
Mov34 family protein.
  
     0.661
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
Server load: low (10%) [HD]