Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB66143.1Heme biosynthesis protein related to NirL and NirH. (152 aa)    
Predicted Functional Partners:
AKB64187.1
Radical SAM domain protein.
 
 
 0.904
AKB66145.1
Radical SAM domain heme biosynthesis protein.
 
 
 0.903
AKB66144.1
Heme biosynthesis protein related to NirD and NirG.
 
   
0.836
hemL
Glutamate-1-semialdehyde aminotransferase.
     
 0.639
AKB66138.1
Radical SAM domain heme biosynthesis protein.
 
 
 0.591
AKB66135.1
Siroheme synthase; Precorrin-2 oxidase; Sirohydrochlorin ferrochelatase.
 
   
 0.512
AKB63481.1
Radical SAM domain protein.
 
 
 0.499
AKB66142.1
Hypothetical protein.
       0.466
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
     
 0.427
AKB63394.1
Radical SAM domain protein.
 
 
 0.408
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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