Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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AKB66191.1Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. (216 aa)    
Predicted Functional Partners:
AKB65970.1
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
    0.856
AKB63986.1
UDP-N-acetylmuramoylalanine--D-glutamate ligase.
  
  
 0.610
AKB66209.1
Rieske 2Fe-2S iron-sulfur protein.
    
 0.609
cysS
Cysteinyl-tRNA synthetase.
   
 
 0.581
hemL
Glutamate-1-semialdehyde aminotransferase.
  
  
 0.569
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
  
 0.545
rpl29
LSU ribosomal protein L35e (L29p); Belongs to the universal ribosomal protein uL29 family.
  
    0.512
rpl24
LSU ribosomal protein L26e (L24p); Located at the polypeptide exit tunnel on the outside of the subunit.
  
    0.506
tyrS
Tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
   
   0.502
AKB63680.1
Hypothetical protein; Belongs to the UPF0235 family.
  
  
 0.477
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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