Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB66241.1Biotin synthase-related enzyme. (331 aa)    
Predicted Functional Partners:
AKB65134.1
OB-fold nucleic acid binding domain protein.
 
     0.805
AKB63861.1
Hypothetical protein.
 
     0.772
AKB66495.1
Putative transcriptional regulator with an HTH domain protein.
  
     0.595
AKB66121.1
Hypothetical protein.
  
     0.574
AKB64390.1
Hypothetical protein.
  
     0.565
AKB63675.1
Hypothetical protein.
  
     0.544
AKB65534.1
Chorismate mutase I.
  
     0.531
AKB63804.1
Hypothetical protein.
  
     0.524
AKB64580.1
PUA-PAPS reductase like fusion.
 
     0.522
AKB63618.1
PUA-PAPS reductase like fusion.
 
     0.516
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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