Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB66250.1Aldo/keto reductase. (398 aa)    
Predicted Functional Partners:
AKB64405.1
Membrane protein, putative.
   
    0.764
AKB64438.1
Integral membrane protein.
  
    0.731
AKB65153.1
Alcohol dehydrogenase.
  
    0.728
AKB64680.1
Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps.
  
    0.717
AKB63569.1
Kef-type transport system 2 (probable substrate potassium), subunit 2.
  
    0.713
AKB63573.1
Kef-type transport system 2 (probable substrate potassium), subunit 1.
  
    0.713
AKB65971.1
Glutathione-regulated potassium-efflux system protein KefC.
  
    0.713
AKB66251.1
Transcriptional regulator, TetR family.
 
     0.669
AKB65588.1
Putative cobalt transporter in sulfate-reducing delta-proteobacteria.
   
    0.629
AKB63503.1
Cytochrome C-type biogenesis protein (ccdA), conjectural.
   
    0.587
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.