Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB66259.1Ribose-1,5-bisphosphate isomerase; Belongs to the eIF-2B alpha/beta/delta subunits family. (307 aa)    
Predicted Functional Partners:
rbcL
Ribulose-1,5-bisphosphate carboxylase, Type III; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily.
 
  
 0.995
AKB64439.1
AMP phosphohydrolase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
 
  
 0.979
AKB66072.1
Eukaryotic translation initiation factor 2 alpha subunit.
   
 0.968
AKB65537.1
Cytidine kinase; Belongs to the carbohydrate kinase PfkB family.
  
 
 0.939
AKB63202.1
Translation elongation factor 1 alpha-related protein.
   
 0.920
eif2g
Eukaryotic translation initiation factor 2 gamma subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
   
 0.920
AKB63330.1
Glucose-1-phosphate thymidylyltransferase.
   
 0.837
AKB64120.1
Mannose-1-phosphate guanylyltransferase.
   
 0.837
AKB64194.1
Glucose-1-phosphate thymidylyltransferase.
   
 0.837
AKB64197.1
Glucose-1-phosphate thymidylyltransferase.
   
 0.837
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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