| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKB65605.1 | AKB66327.1 | MSMAS_2409 | MSMAS_3131 | Hypothetical protein. | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | 0.546 |
| AKB65605.1 | rpl2 | MSMAS_2409 | MSMAS_2557 | Hypothetical protein. | LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.963 |
| AKB65605.1 | rtcA | MSMAS_2409 | MSMAS_0017 | Hypothetical protein. | RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. | 0.430 |
| AKB65605.1 | rtcB | MSMAS_2409 | MSMAS_3130 | Hypothetical protein. | RNA-2',3'-PO4:RNA-5'-OH ligase; Belongs to the RtcB family. | 0.524 |
| AKB66097.1 | AKB66327.1 | MSMAS_2901 | MSMAS_3131 | Phosphoribosyl transferase domain protein. | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | 0.448 |
| AKB66097.1 | rtcB | MSMAS_2901 | MSMAS_3130 | Phosphoribosyl transferase domain protein. | RNA-2',3'-PO4:RNA-5'-OH ligase; Belongs to the RtcB family. | 0.432 |
| AKB66306.1 | AKB66327.1 | MSMAS_3110 | MSMAS_3131 | Hypothetical protein. | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | 0.560 |
| AKB66306.1 | AKB66447.1 | MSMAS_3110 | MSMAS_3251 | Hypothetical protein. | Hypothetical protein. | 0.514 |
| AKB66306.1 | rtcB | MSMAS_3110 | MSMAS_3130 | Hypothetical protein. | RNA-2',3'-PO4:RNA-5'-OH ligase; Belongs to the RtcB family. | 0.558 |
| AKB66327.1 | AKB65605.1 | MSMAS_3131 | MSMAS_2409 | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | Hypothetical protein. | 0.546 |
| AKB66327.1 | AKB66097.1 | MSMAS_3131 | MSMAS_2901 | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | Phosphoribosyl transferase domain protein. | 0.448 |
| AKB66327.1 | AKB66306.1 | MSMAS_3131 | MSMAS_3110 | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | Hypothetical protein. | 0.560 |
| AKB66327.1 | AKB66328.1 | MSMAS_3131 | MSMAS_3132 | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.882 |
| AKB66327.1 | AKB66329.1 | MSMAS_3131 | MSMAS_3133 | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase. | 0.720 |
| AKB66327.1 | AKB66447.1 | MSMAS_3131 | MSMAS_3251 | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | Hypothetical protein. | 0.514 |
| AKB66327.1 | prf1 | MSMAS_3131 | MSMAS_3316 | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. | 0.546 |
| AKB66327.1 | rpl2 | MSMAS_3131 | MSMAS_2557 | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.564 |
| AKB66327.1 | rtcA | MSMAS_3131 | MSMAS_0017 | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. | 0.761 |
| AKB66327.1 | rtcB | MSMAS_3131 | MSMAS_3130 | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | RNA-2',3'-PO4:RNA-5'-OH ligase; Belongs to the RtcB family. | 0.997 |
| AKB66328.1 | AKB66327.1 | MSMAS_3132 | MSMAS_3131 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | 0.882 |
