STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB66335.1Aconitate hydratase. (935 aa)    
Predicted Functional Partners:
AKB66336.1
Citrate synthase (si).
 
 0.999
AKB65912.1
Malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.995
AKB63494.1
3-isopropylmalate dehydrogenase.
 
 0.985
AKB63495.1
2-isopropylmalate synthase.
  
 0.955
AKB65473.1
Superoxide dismutase (Mn/Fe); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.895
AKB65409.1
NADH-quinone oxidoreductase subunit C/D.
  
 0.894
AKB65410.1
NADH-quinone oxidoreductase subunit C/D.
  
 0.894
rpl2
LSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
 
 0.893
AKB63631.1
Beta-ketoacyl synthase/thiolase.
  
 0.873
AKB63863.1
Coenzyme B synthesis from 2-oxoglutarate: steps 5, 9, and 13.
 
 0.863
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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