STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB66347.1Cysteine desulfurase. (393 aa)    
Predicted Functional Partners:
AKB65924.1
Scaffold protein.
  
 0.988
AKB64417.1
Scaffold protein.
  
 0.983
AKB63409.1
Iron-sulfur cluster assembly protein SufB.
 
 0.961
AKB63410.1
Iron-sulfur cluster assembly ATPase protein SufC.
 
 
 0.953
AKB65542.1
Thioredoxin reductase.
 
 
 0.934
AKB65827.1
Iron-sulfur cluster assembly ATPase protein SufC.
 
 
 0.933
AKB65828.1
Iron-sulfur cluster assembly protein SufB.
 
 0.925
AKB66331.1
Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
  
 
 0.825
thiI
tRNA S(4)U 4-thiouridine synthase (former ThiI); Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
  
 0.782
fdhD
Formate dehydrogenase chain D; Required for formate dehydrogenase (FDH) activity. Belongs to the FdhD family.
 
  
  0.781
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.