STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
matArchaeal S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (398 aa)    
Predicted Functional Partners:
AKB66504.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
     
 0.990
AKB64039.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
     
 0.977
AKB66505.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
     
 0.977
AKB65805.1
Archaeal S-adenosylmethionine synthetase.
  
  
 
0.906
AKB64795.1
Methionine gamma-lyase.
    
  0.901
AKB64218.1
DNA-cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
     
  0.900
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
  
    0.604
AKB63629.1
Hypothetical protein.
 
     0.583
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
       0.566
hisB
Imidazoleglycerol-phosphate dehydratase.
       0.564
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.