STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB66375.13-isopropylmalate dehydrogenase. (375 aa)    
Predicted Functional Partners:
AKB63840.1
Acetolactate synthase small subunit.
  
 0.984
AKB63839.1
Acetolactate synthase large subunit.
 
 0.969
AKB65078.1
Acetolactate synthase large subunit; Belongs to the TPP enzyme family.
 
 0.969
leuD
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
 
 0.967
leuC-2
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 0.964
leuC
Coenzyme B synthesis from 2-oxoglutarate: steps 4, 7, 8, 11, and 12 (large subunit); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 0.957
AKB64080.1
2-oxoglutarate oxidoreductase, beta subunit.
  
 
 0.942
AKB66520.1
Pyruvate:ferredoxin oxidoreductase, beta subunit.
  
 
 0.942
AKB64079.1
2-oxoglutarate oxidoreductase, alpha subunit.
    
 0.933
AKB66519.1
Pyruvate:ferredoxin oxidoreductase, alpha subunit.
    
 0.933
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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