Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB66400.1Lead, cadmium, zinc and mercury transporting ATPase; Copper-translocating P-type ATPase. (649 aa)    
Predicted Functional Partners:
AKB65646.1
Arsenical resistance operon repressor.
 
  
 0.506
AKB65569.1
Lead, cadmium, zinc and mercury transporting ATPase; Copper-translocating P-type ATPase.
    
 0.488
AKB65571.1
Mercury ion binding protein.
    
 0.488
AKB63428.1
Sodium/potassium-transporting ATPase, alpha subunit.
  
 0.483
AKB63600.1
Cation-transporting ATPase.
  
 0.483
AKB63667.1
Cation-transporting ATPase, E1-E2 family.
  
 0.483
AKB64815.1
Cation-transporting P-type ATPase.
  
 0.483
AKB65359.1
Cation-transporting ATPase, E1-E2 family.
  
 0.483
AKB66402.1
Ca ion P-type ATPase.
  
 0.483
AKB63803.1
COG1779: C4-type Zn finger.
      
 0.478
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
Server load: low (16%) [HD]