STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pylSPyrrolysyl-tRNA synthetase; Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG. (454 aa)    
Predicted Functional Partners:
AKB66417.1
Pyrrolysine synthetase.
 
   
 0.899
AKB66418.1
Proline reductase for pyrrolysine biosynthesis.
 
   
 0.889
AKB66416.1
Proline 2-methylase for pyrrolysine biosynthesis.
 
   
 0.877
tyrS
Tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
      
 0.797
tuf
Translation elongation factor 1 alpha subunit; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
      
 0.793
AKB65832.1
Trimethylamine:corrinoid methyltransferase; Pyrrolysine-containing; Belongs to the trimethylamine methyltransferase family.
 
   
 0.761
AKB64542.1
Monomethylamine:corrinoid methyltransferase; Pyrrolysine-containing.
 
   
 0.748
AKB66423.1
Monomethylamine:corrinoid methyltransferase; Pyrrolysine-containing.
 
   
 0.747
AKB66178.1
Choline permease LicB.
  
   
 0.694
AKB65834.1
Choline permease LicB.
  
   
 0.685
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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