Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKB66416.1Proline 2-methylase for pyrrolysine biosynthesis. (349 aa)    
Predicted Functional Partners:
AKB66417.1
Pyrrolysine synthetase.
 
 
 0.999
AKB66418.1
Proline reductase for pyrrolysine biosynthesis.
 
   
 0.992
pylS
Pyrrolysyl-tRNA synthetase; Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG.
 
   
 0.988
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
  
 0.933
AKB63568.1
Lysine 2,3-aminomutase.
    
 0.849
AKB66343.1
ATP-utilizing enzyme of the PP-loop superfamily.
  
    0.848
AKB64405.1
Membrane protein, putative.
  
    0.756
AKB65832.1
Trimethylamine:corrinoid methyltransferase; Pyrrolysine-containing; Belongs to the trimethylamine methyltransferase family.
 
   
 0.729
AKB63459.1
Substrate-specific component BioY of biotin ECF transporter.
  
  
 0.684
AKB63569.1
Kef-type transport system 2 (probable substrate potassium), subunit 2.
  
    0.678
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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