STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB66416.1Proline 2-methylase for pyrrolysine biosynthesis. (349 aa)    
Predicted Functional Partners:
AKB66417.1
Pyrrolysine synthetase.
 
 
 0.998
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
  
 0.937
AKB66418.1
Proline reductase for pyrrolysine biosynthesis.
 
   
 0.912
pylS
Pyrrolysyl-tRNA synthetase; Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG.
 
   
 0.877
AKB63568.1
Lysine 2,3-aminomutase.
    
 0.869
carB
Carbamoyl-phosphate synthase large chain; Belongs to the CarB family.
  
 
 0.686
nadA
Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
 
  
 0.666
AKB63427.1
Methylcobalamin:coenzyme M methyltransferase, methanol-specific.
 
 
 0.658
AKB66343.1
ATP-utilizing enzyme of the PP-loop superfamily.
  
    0.649
AKB64321.1
Methylcobalamin:coenzyme M methyltransferase, methanol-specific.
 
 
 0.643
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.