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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
secDProtein-export membrane protein SecD; Involved in protein export. (566 aa)    
Predicted Functional Partners:
secF
Protein-export membrane protein SecF; Involved in protein export.
 
 0.999
AKB66515.1
Signal peptidase I.
 
  
 0.886
AKB66458.1
Archaeosortase A.
  
   
 0.843
AKB64416.1
Tetrahydromethanopterin:alpha-L-glutamate ligase.
 
  
 0.741
AKB65549.1
Coenzyme gamma-F420-2:alpha-L-glutamate ligase.
 
  
 0.738
pheT
Phenylalanyl-tRNA synthetase beta chain.
 
 
 
 0.704
eif5a
Eukaryotic translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
 
 
 0.703
AKB66433.1
Replication factor C small subunit.
       0.654
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
 
  
 0.649
alaS
Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
 
    0.645
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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