STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB66472.1ATP-dependent RNA helicase, EIF-4A family. (852 aa)    
Predicted Functional Partners:
rpl1
LSU ribosomal protein L10Ae (L1p); Binds directly to 23S rRNA. Probably involved in E site tRNA release.
    
 0.908
AKB63291.1
ATP-dependent DNA helicase RecQ.
   
 
 0.903
AKB63211.1
Replication factor A (ssDNA-binding protein).
 
 
 0.884
rpl40e
LSU ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
  
 
  0.866
AKB64203.1
Replication protein A (two OB fold, one zinc finger).
 
 
 0.853
AKB66124.1
Replication factor-A protein 1.
 
 
 0.845
AKB64312.1
DNA topoisomerase I.
  
 
 0.828
pcn
DNA polymerase sliding clamp protein PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
  
 
 
 0.808
smc
Chromosome partition protein smc; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
 
 0.805
radA
DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
  
 
 0.744
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
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