Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKB66485.1Alpha/beta superfamily. (326 aa)    
Predicted Functional Partners:
secG
Preprotein translocase subunit SecG; Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
       0.725
mutS2
DNA mismatch repair protein; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
 
     0.673
AKB64987.1
Cell surface protein.
  
     0.519
AKB65984.1
Phenylacetic acid degradation protein paaI.
 
  
 0.490
AKB63581.1
GDP-mannose mannosyl hydrolase.
 
  
 0.482
AKB64762.1
Hypothetical protein.
 
   
 0.460
AKB64639.1
Putative membrane protein.
 
     0.454
lon
ATP-dependent protease La Type I; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
 
  
 0.453
AKB64642.1
Putative membrane protein.
 
     0.441
AKB64756.1
Putative hydrolase.
 
 
 0.435
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
Server load: low (12%) [HD]