close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKB66519.1Pyruvate:ferredoxin oxidoreductase, alpha subunit. (402 aa)    
Predicted Functional Partners:
AKB66517.1
Pyruvate:ferredoxin oxidoreductase, gamma subunit.
 
 0.999
AKB66518.1
Pyruvate:ferredoxin oxidoreductase, delta subunit.
 
 0.999
AKB66520.1
Pyruvate:ferredoxin oxidoreductase, beta subunit.
 0.999
AKB64080.1
2-oxoglutarate oxidoreductase, beta subunit.
 
 0.993
AKB64407.1
CO dehydrogenase iron-sulfur protein CooF.
  
 
 0.982
AKB64140.1
Acetyl-CoA synthetase (ADP-forming) alpha chain.
  
 0.976
AKB65180.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.974
AKB63798.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.973
AKB66050.1
Pyruvate carboxyl transferase subunit B.
    
 0.973
AKB66049.1
Pyruvate carboxyl transferase subunit A.
  
 
  0.971
Your Current Organism:
Methanosarcina mazei
NCBI taxonomy Id: 213585
Other names: M. mazei S-6, Methanosarcina mazei S-6
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.