STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (318 aa)    
Predicted Functional Partners:
SHE58513.1
N-acetylglutamate kinase.
  
  0.999
argD
acetylornithine/N-succinyldiaminopimelate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
 
 0.995
argH
Argininosuccinate lyase.
 
  
 0.994
SHE58439.1
Argininosuccinate synthase.
 
  
 0.993
SHE58397.1
N-acetylornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
 
 
 0.992
SHE58483.1
Acetylornithine deacetylase.
 
 0.983
SHE54458.1
Acetylornithine/succinyldiaminopimelate/putresci ne aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.879
carB
Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family.
  
  
 0.672
dapE
Succinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
  
 0.663
SHE27121.1
Aspartate kinase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
 
  
 0.656
Your Current Organism:
Thermomonas hydrothermalis
NCBI taxonomy Id: 213588
Other names: ATCC BAA-470, DSM 14834, T. hydrothermalis, Thermomonas hydrothermalis Alves et al. 2003, strain SGM-6
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