STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHF01187.1Putative Zn-dependent protease, contains TPR repeats; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state. (531 aa)    
Predicted Functional Partners:
SHF01220.1
Two-component system, OmpR family, phosphate regulon response regulator PhoB.
       0.640
SHF08444.1
Methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor.
    
  0.603
ribB
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
  0.588
SHF01159.1
Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
       0.586
SHF01132.1
Alkylhydroperoxidase AhpD family core domain-containing protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
       0.585
SHE32235.1
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB.
  
 
   0.537
SHF01253.1
Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR.
    
  0.533
SHE27402.1
Lipoprotein NlpD.
  
 
   0.529
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
       0.476
SHE74913.1
Diguanylate cyclase (GGDEF) domain-containing protein.
   
 
  0.441
Your Current Organism:
Thermomonas hydrothermalis
NCBI taxonomy Id: 213588
Other names: ATCC BAA-470, DSM 14834, T. hydrothermalis, Thermomonas hydrothermalis Alves et al. 2003, strain SGM-6
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