STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (389 aa)    
Predicted Functional Partners:
SHF35122.1
Phosphate acetyltransferase.
 
 0.998
SHF36368.1
Phosphate acetyl/butaryl transferase.
 
 
 0.982
SHE73741.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
  
 
 0.953
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.948
SHF35151.1
Polyhydroxyalkanoate synthase.
  
 0.929
SHF02496.1
Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.
  
 
 0.926
SHE27041.1
Acylphosphatase.
     
 0.883
SHF35066.1
Enoyl-[acyl-carrier-protein] reductase [NADH].
 
  
 0.883
SHE72108.1
Malate synthase.
   
 
 0.830
SHE72069.1
Isocitrate lyase.
   
  
 0.786
Your Current Organism:
Thermomonas hydrothermalis
NCBI taxonomy Id: 213588
Other names: ATCC BAA-470, DSM 14834, T. hydrothermalis, Thermomonas hydrothermalis Alves et al. 2003, strain SGM-6
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