Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RUM_03340Stage V sporulation protein AD. (341 aa)    
Predicted Functional Partners:
RUM_03330
Stage V sporulation protein AE.
 
  
 0.979
RUM_23370
Stage V sporulation protein AC.
 
  
 0.941
gpr
Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination.; Belongs to the peptidase A25 family.
  
  
 0.906
RUM_03320
Predicted membrane protein.
 
  
 0.887
RUM_05170
Transcriptional regulator, AbrB family.
  
   
 0.813
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
  
 0.810
RUM_23190
Stage IV sporulation protein B.
  
  
 0.796
RUM_03970
Stage IV sporulation protein A.
  
   
 0.795
RUM_24020
Bacillus/Clostridium GerA spore germination protein.
  
  
 0.790
RUM_23170
Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.782
Your Current Organism:
Ruminococcus champanellensis
NCBI taxonomy Id: 213810
Other names: R. champanellensis 18P13 = JCM 17042, Ruminococcus champanellensis 18P13, Ruminococcus champanellensis 18P13 = JCM 17042, Ruminococcus champanellensis DSM 18848, Ruminococcus champanellensis JCM 17042, Ruminococcus champanellensis JCM 17042 = 18P13, Ruminococcus sp. 18P13
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.