node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RUM_07210 | RUM_10900 | RUM_07210 | RUM_10900 | Prepilin-type N-terminal cleavage/methylation domain. | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | 0.467 |
RUM_07210 | RUM_11910 | RUM_07210 | RUM_11910 | Prepilin-type N-terminal cleavage/methylation domain. | AAA domain (Cdc48 subfamily). | 0.584 |
RUM_07210 | dnaK | RUM_07210 | RUM_03470 | Prepilin-type N-terminal cleavage/methylation domain. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.965 |
RUM_07210 | groS | RUM_07210 | RUM_04950 | Prepilin-type N-terminal cleavage/methylation domain. | Co-chaperonin GroES (HSP10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.537 |
RUM_07210 | grpE | RUM_07210 | RUM_03460 | Prepilin-type N-terminal cleavage/methylation domain. | Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...] | 0.808 |
RUM_07210 | htpG | RUM_07210 | RUM_22830 | Prepilin-type N-terminal cleavage/methylation domain. | Molecular chaperone, HSP90 family; Molecular chaperone. Has ATPase activity. | 0.920 |
RUM_10900 | RUM_07210 | RUM_10900 | RUM_07210 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | Prepilin-type N-terminal cleavage/methylation domain. | 0.467 |
RUM_10900 | RUM_11910 | RUM_10900 | RUM_11910 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | AAA domain (Cdc48 subfamily). | 0.643 |
RUM_10900 | dnaJ | RUM_10900 | RUM_03480 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.648 |
RUM_10900 | dnaK | RUM_10900 | RUM_03470 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.674 |
RUM_10900 | groS | RUM_10900 | RUM_04950 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | Co-chaperonin GroES (HSP10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.458 |
RUM_10900 | grpE | RUM_10900 | RUM_03460 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...] | 0.679 |
RUM_10900 | htpG | RUM_10900 | RUM_22830 | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | Molecular chaperone, HSP90 family; Molecular chaperone. Has ATPase activity. | 0.599 |
RUM_11910 | RUM_07210 | RUM_11910 | RUM_07210 | AAA domain (Cdc48 subfamily). | Prepilin-type N-terminal cleavage/methylation domain. | 0.584 |
RUM_11910 | RUM_10900 | RUM_11910 | RUM_10900 | AAA domain (Cdc48 subfamily). | Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. | 0.643 |
RUM_11910 | RUM_19480 | RUM_11910 | RUM_19480 | AAA domain (Cdc48 subfamily). | Hypothetical protein. | 0.573 |
RUM_11910 | RUM_22200 | RUM_11910 | RUM_22200 | AAA domain (Cdc48 subfamily). | ATP-dependent Clp protease proteolytic subunit ClpP. | 0.673 |
RUM_11910 | clpP | RUM_11910 | RUM_08610 | AAA domain (Cdc48 subfamily). | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.779 |
RUM_11910 | dnaJ | RUM_11910 | RUM_03480 | AAA domain (Cdc48 subfamily). | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.695 |
RUM_11910 | dnaK | RUM_11910 | RUM_03470 | AAA domain (Cdc48 subfamily). | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.822 |