Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
asnCRegulatory protein; Similar to the Escherichia coli regulator of AnsA: AsnC SW:ASNC_ECOLI (P03809) (152 aa) fasta scores: E(): 0,84.8% id in 151 aa. (153 aa)    
Predicted Functional Partners:
YPO3146
Similar to Zymomonas mobilis glutamate uptake regulatory protein Grp SW:GRP_ZYMMO (P74996) (164 aa) fasta scores: E(): 6.8e-27, 42.8% id in 152 aa, and to Escherichia coli hypothetical transcriptional regulator YbaO SW:YBAO_ECOLI (P54986) (152 aa) fasta scores: E(): 0,74.8% id in 151 aa.
  
     0.769
YPO1651
AsnC-family transcriptional regulatory protein; Similar to Bacillus subtilis transcriptional regulator LrpB SW:LRPB_BACSU (P96653) (149 aa) fasta scores: E(): 6.8e-08, 27.1% id in 118 aa, and to Pseudomonas aeruginosa TR:AAG05965 (EMBL:AE004686) (145 aa) fasta scores: E(): 3.5e-28, 53.5% id in 142 aa.
  
     0.763
nifJ
Similar to Escherichia coli probable pyruvate-flavodoxin oxidoreductase YdbK SW:NIFJ_ECOLI (P52647) (1174 aa) fasta scores: E(): 0, 80.5% id in 1177 aa, and to Klebsiella pneumoniae pyruvate-flavodoxin oxidoreductase NifJ SW:NIFJ_KLEPN (P03833) (1171 aa) fasta scores: E(): 0, 48.0% id in 1184 aa.
    
 0.710
asnA
Similar to Escherichia coli aspartate-ammonia ligase AsnA SW:ASNA_ECOLI (P00963) (330 aa) fasta scores: E(): 0,78.5% id in 330 aa.
 
     0.608
b4390
Similar to Salmonella typhimurium transcriptional regulator NadR SW:NADR_SALTY (P24518) (409 aa) fasta scores: E(): 0, 85.0% id in 406 aa, and to Escherichia coli transcriptional regulator NadR SW:NADR_ECOLI (P27278) (410 aa) fasta scores: E(): 0, 83.7% id in 406 aa.
   
  
 0.552
YPO0001
Putative flavoprotein; Similar to the FMN-binding domain of many flavoproteins e.g. Salmonella typhimurium sulfite reductase [NADPH] flavoprotein alpha-component CysJ SW:CYSJ_SALTY (P38039) (598 aa) fasta scores: E(): 3.8e-06, 32.0% id in 128 aa. Also highly similar over entire range to Escherichia coli MioC protein, the fuction of which in a chromosomal context, is unknown SW:MIOC_ECOLI (P03817) (146 aa) fasta scores: E(): 0, 66.9% id in 145 aa.
  
    0.549
uvrY
Response regulator protein; Similar to Escherichia coli UvrY protein SW:UVRY_ECOLI (P07027) (218 aa) fasta scores: E(): 0, 82.9% id in 217 aa, and to Salmonella typhimurium SirA TR:P96058 (EMBL:U67869) (218 aa) fasta scores: E(): 0, 83.9% id in 217 aa.
      
 0.540
poaA
Bifunctional PutA protein [includes: proline dehydrogenase and delta-1-pyrroline-5-carboxylate; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
     
 0.510
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
  
 
 0.509
cysG-2
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
 
 0.509
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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