Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
YPO0331Hypothetical protein; No significant database hits. (60 aa)    
Predicted Functional Partners:
b3903
Similar to Escherichia coli L-rhamnose isomerase RhaA SW:RHAA_ECOLI (P32170) (419 aa) fasta scores: E(): 0,85.2% id in 418 aa.
       0.567
b3904
Rhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. Belongs to the rhamnulokinase family.
       0.567
b3902
Rhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. Belongs to the aldolase class II family. RhaD subfamily.
       0.556
YPO1102
Similar to Escherichia coli hypothetical protein YfjG SW:YFJG_ECOLI (P52121) (158 aa) fasta scores: E(): 0,79.3% id in 145 aa, and to Vibrio cholerae hypothetical protein VC0849 SW:Y849_VIBCH (P52122) (144 aa) fasta scores: E(): 0, 69.0% id in 142 aa.
      
 0.488
YPO2159
Similar to Escherichia coli hypothetical protein YeaC SW:YEAC_ECOLI (P76231) (90 aa) fasta scores: E(): 7.7e-23, 70.7% id in 82 aa, and to Vibrio cholerae hypothetical protein VC1996 TR:Q9KQK2 (EMBL:AE004274) (95 aa) fasta scores: E(): 1.5e-16, 46.2% id in 91 aa.
      
 0.488
YPO2327
Putative lipoprotein; Similar to Escherichia coli hypothetical protein YnbE SW:YNBE_ECOLI (P76075) (61 aa) fasta scores: E(): 1.7e-10, 66.0% id in 50 aa, and to Pseudomonas aeruginosa hypothetical protein PA5306 TR:AAG08691 (EMBL:AE004943) (63 aa) fasta scores: E(): 2.3e-06, 44.4% id in 54 aa.
      
 0.488
b3905
L-rhamnose operon regulatory protein; Activates expression of the rhaBAD and rhaT operons.
       0.433
YPO0327
Probable alcohol dehydrogenase; Similar to Bacillus methanolicus NAD-dependent methanol dehydrogenase Mdh SW:MEDH_BACMT (P31005) (380 aa) fasta scores: E(): 0, 42.9% id in 378 aa and to Escherichia coli probable alcohol dehydrogenase YiaY SW:ADH2_ECOLI (P37686) (382 aa) fasta scores: E(): 0, 43.6% id in 376 aa.
       0.429
rhaM
Conserved hypothetical protein; Involved in the anomeric conversion of L-rhamnose.
       0.419
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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