STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
b0033Similar to Escherichia coli carbamoyl-phosphate synthase large chain CarB SW:CARB_ECOLI (P00968) (1072 aa) fasta scores: E(): 0, 92.6% id in 1072 aa, and to Salmonella typhimurium carbamoyl-phosphate synthase large chain CarB SW:CARB_SALTY (P14846) (1074 aa) fasta scores: E(): 0, 92.7% id in 1072 aa. (1077 aa)    
Predicted Functional Partners:
b0032
Similar to Escherichia coli carbamoyl-phosphate synthase small chain CarA SW:CARA_ECOLI (P00907) (382 aa) fasta scores: E(): 0, 86.4% id in 381 aa, and to Salmonella typhimurium carbamoyl-phosphate synthase small chain CarA SW:CARA_SALTY (P14845) (382 aa) fasta scores: E(): 0, 86.4% id in 381 aa; Belongs to the CarA family.
 0.999
pyrB
Similar to Escherichia coli aspartate carbamoyltransferase catalytic chain PyrB SW:PYRB_ECOLI (P00479) (310 aa) fasta scores: E(): 0, 84.8% id in 310 aa,and to Erwinia herbicola aspartate transcarbamylase catalytic subunit PyrB TR:Q9RMS8 (EMBL:AF190426) (311 aa) fasta scores: E(): 0, 85.9% id in 311 aa.
 
 0.999
argG
Similar to Escherichia coli argininosuccinate synthase ArgG SW:ASSY_ECOLI (P22767) (446 aa) fasta scores: E(): 0, 90.5% id in 440 aa, and to Neisseria meningitidis argininosuccinate synthase ArgG or Nma0303 TR:Q9JWM1 (EMBL:AL162752) (447 aa) fasta scores: E(): 0, 80.7% id in 440 aa; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
 
 
 0.995
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 
 0.994
argI
Ornithine carbamoyltransferase chain I; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
 
 0.994
pyrI
Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase.
  
 
  0.993
aspB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SW:GLTB_ECOLI (P09831) (1517 aa) fasta scores: E(): 0, 87.4% id in 1497 aa, and to Vibrio cholerae glutamate synthase, large subunit Vc2376 TR:Q9KPJ1 (EMBL:AE004308) (1487 aa) fasta scores: E(): 0, 73.7% id in 1488 aa.
  
 
 0.981
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 0.973
glnA
Glutamine synthetase; Highly similar to Escherichia coli glutamine synthetase GlnA SW:GLNA_ECOLI (P06711) (468 aa) fasta scores: E(): 0, 91.5% id in 468 aa.
 
 
 0.963
glmS
Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 0.962
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.