STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YPO0683Similar to Escherichia coli biopolymer transport protein ExbD SW:EXBD_ECOLI (P18784) (141 aa) fasta scores: E(): 0, 67.9% id in 140 aa, and to Pseudomonas putida biopolymer transport protein ExbD SW:EXBD_PSEPU (Q05606) (142 aa) fasta scores: E(): 2.6e-31, 67.1% id in 140 aa. (143 aa)    
Predicted Functional Partners:
YPO0682
MotA/TolQ/ExbB proton channel family protein; Similar to Escherichia coli biopolymer transport protein ExbB SW:EXBB_ECOLI (P18783) (244 aa) fasta scores: E(): 0, 70.8% id in 236 aa, and to Pseudomonas putida biopolymer transport protein ExbB SW:EXBB_PSEPU (Q05605) (329 aa) fasta scores: E(): 0, 62.7% id in 236 aa.
 
 
 0.999
tonB
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 0.989
tolQ
TolQ colicin import protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
 
 
 0.980
YPO3918
Putative membrane protein; Similar to Pseudomonas putida ferric-siderophore transport protein TonB SW:TONB_PSEPU (Q05613) (243 aa) fasta scores: E(): 1.5e-13, 32.0% id in 253 aa, and to Haemophilus influenzae energy transducer protein TonB SW:TONB_HAEIN (P42872) (270 aa) fasta scores: E(): 1.3e-08,27.5% id in 280 aa.
 
 
 0.970
YPO1528
Similar to Escherichia coli ferric iron reductase protein FhuF SW:FHUF_ECOLI (P39405) (262 aa) fasta scores: E(): 8.4e-33, 35.0% id in 246 aa.
   
  
 0.877
infB
Translation initiation factor IF2-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
 
 0.758
tolB
TolB colicin import protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
 
  
 0.729
YPO0701
Periplasmic binding protein; Similar to Escherichia coli siderophore ferrienterobactin-binding periplasmic protein precursor FepB SW:FEPB_ECOLI (P14609) (318 aa) fasta scores: E(): 0,53.9% id in 293 aa, and to Pseudomonas aeruginosa ferrienterobactin-binding periplasmic protein FepB TR:AAG07546 (EMBL:AE004832) (301 aa) fasta scores: E(): 6.1e-32, 38.1% id in 278 aa.
   
  
 0.718
tolA
TolA colicin import membrane protein; Similar to Escherichia coli TolA protein SW:TOLA_ECOLI (P19934) (421 aa) fasta scores: E(): 5.1e-27,57.9% id in 423 aa, and to Pseudomonas aeruginosa TolA protein SW:TOLA_PSEAE (P50600) (347 aa) fasta scores: E(): 6.6e-09, 33.2% id in 319 aa.
  
   0.659
YPO1011
Similar to Azospirillum irakense putative outer membrane salicin receptor salC TR:Q9LAE4 (EMBL:AF143227) (726 aa) fasta scores: E(): 0, 25.3% id in 730 aa, and to Escherichia coli probable TonB-dependent receptor YncD SW:YNCD_ECOLI (P76115) (700 aa) fasta scores: E(): 2.1e-15,22.9% id in 721 aa.
 
  
 0.586
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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