STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
YPO0744Putative flagellar biogenesis protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family. (156 aa)    
Predicted Functional Partners:
fliA
Similar to Salmonella typhimurium RNA polymerase sigma factor for flagellar operon FliA SW:FLIA_SALTY (P17168) (239 aa) fasta scores: E(): 4e-20, 35.0% id in 217 aa, and to Vibrio parahaemolyticus RNA polymerase sigma factor for flagellar operon LafS SW:LAFS_VIBPA (Q03474) (242 aa) fasta scores: E(): 2.5e-25, 40.3% id in 216 aa; Belongs to the sigma-70 factor family.
  
  
 0.962
motA
Putative flagellar motor transmembrane channel protein; Similar to Escherichia coli chemotaxis protein MotA SW:MOTA_ECOLI (P09348) (295 aa) fasta scores: E(): 0, 37.9% id in 277 aa, and to Vibrio parahaemolyticus chemotaxis protein LafT SW:LAFT_VIBPA (Q03477) (285 aa) fasta scores: E(): 0, 56.4% id in 280 aa.
  
  
 0.951
YPO0743
Similar to Escherichia coli flagellar hook-length control protein FliK SW:FLIK_ECOLI (P52614) (375 aa) fasta scores: E(): 0.0085, 22.6% id in 381 aa.
  
  
 0.950
fla-9
Flagellar protein FlgJ; Similar to Salmonella typhimurium flagellar protein FlgJ or FlaZ or Fla FX SW:FLGJ_SALTY (P15931) (316 aa) fasta scores: E(): 0, 60.4% id in 316 aa, and to Escherichia coli flagellar protein FlgJ or FlaZ or Fla FX SW:FLGJ_ECOLI (P75942) (313 aa) fasta scores: E(): 0, 57.4% id in 317 aa.
  
  
 0.948
lafU
Similar to Escherichia coli chemotaxis protein MotB protein SW:MOTB_ECOLI (P09349) (308 aa) fasta scores: E(): 1.1e-23, 32.6% id in 310 aa, and to Vibrio parahaemolyticus chemotaxis protein LafU SW:LAFU_VIBPA (Q03478) (330 aa) fasta scores: E(): 0, 40.1% id in 297 aa.
  
 
 0.933
fliD
Putative flagellar hook-associated protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
  
 0.927
fliS
Similar to Vibrio parahaemolyticus flagellar protein LafC TR:P74950 (EMBL:U52957) (128 aa) fasta scores: E(): 9.5e-18, 44.3% id in 122 aa, and to Salmonella typhimurium flagellar protein FliS SW:FLIS_SALTY (P26609) (135 aa) fasta scores: E(): 1.5e-12, 36.1% id in 119 aa.
  
  
 0.924
fliO
Flagellar protein FliO; Similar to Escherichia coli flagellar protein FliO SW:FLIO_ECOLI (P22586) (101 aa) fasta scores: E(): 3.5e-10,50.6% id in 87 aa, and to Erwinia carotovora MopB protein SW:MOPB_ERWCA (P34199) (140 aa) fasta scores: E(): 7.2e-26,65.0% id in 117 aa.
  
 
 0.922
CheC2
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
  
 
 0.911
fliM
Similar to Rhodobacter sphaeroides flagellar switch protein FliM TR:O85118 (EMBL:AF044254) (323 aa) fasta scores: E(): 0.29, 20.7% id in 276 aa, and to Buchnera aphidicola (subsp Acyrthosiphon pisum) putative motor switch protein FliM TR:BAB12800 (EMBL:AP001118) (315 aa) fasta scores: E(): 0.12, 20.2% id in 213 aa.
  
 
 0.887
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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