STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YPO0772Putative membrane protein; Similar to Yersinia enterocolitica,high-pathogenicity island, signal transducer protein Irp8 TR:Q9X9I7 (EMBL:AJ132668) (462 aa) fasta scores: E(): 3.9e-22, 27.9% id in 416 aa, and to Yersinia pestis protein hypothetical protein YbtX TR:Q9ZC28 (EMBL:AL031866) (462 aa) fasta scores: E(): 8e-22, 27.1% id in 421 aa. (434 aa)    
Predicted Functional Partners:
YPO0774
Conserved hypothetical protein; Similar to Yersinia enterocolitica high-pathogenicity island protein Irp3 TR:O54512 (EMBL:Y12527) (365 aa) fasta scores: E(): 3.6e-30, 33.7% id in 362 aa, and to Yersinia pestis YbtU protein ybtU TR:Q9Z3C6 (EMBL:AL031866) (365 aa) fasta scores: E(): 3.6e-30, 33.8% id in 364 aa.
  
    0.914
YPO0773
Putative thioesterase; Similar to Pseudomonas aeruginosa probable pyochelin biosynthetic protein PchC TR:AAG07617 (EMBL:AE004840) (251 aa) fasta scores: E(): 1.1e-30, 38.6% id in 236 aa, and to C-terminus of Streptomyces griseus probable cadicidin biosynthesis thioesterase SW:PABT_STRGR (P33586) (361 aa) fasta scores: E(): 6e-25, 36.4% id in 225 aa.
 
    0.850
YPO0776
Putative siderophore biosysnthesis protein; Similar to N-terminus of Yersinia pestis yersiniabactin biogenesis protein Irp2 TR:Q9Z399 (EMBL:AL031866) (2041 aa) fasta scores: E(): 0, 31.1% id in 1659 aa, and to Pseudomonas aeruginosa pyochelin synthetase PchF TR:Q9RFM7 (EMBL:AF184622) (1809 aa) fasta scores: E(): 0, 34.1% id in 1957 aa. and to Vibrio anguillarum anguibactin biosynthesis protein AngR SW:ANGR_VIBAN (P19828) (1048 aa) fasta scores: E(): 0, 32.1% id in 844 aa. CDS contains a glutamine and threonine rich imperfect repeat region, residues 996 to 1065.
 
  
 0.829
menF
Menaquinone-specific isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate.
  
    0.804
YPO0777
Putative siderophore biosysnthesis protein; Similar to the C-terminus of Vibrio anguillarum anguibactin biosynthesis protein AngR SW:ANGR_VIBAN (P19828) (1048 aa) fasta scores: E(): 0, 40.7% id in 553 aa. N-terminus of the CDS is similar to an internal region of Yersinia pestis yersiniabactin biogenesis protein Irp2 TR:Q9Z399 (EMBL:AL031866) (2041 aa) fasta scores: E(): 0,45.1% id in 439 aa.
 
    0.798
YPO0770
ABC-transporter transmembrane protein; Similar to Yersinia enterocolitica,high-pathogenicity island, lipoprotein inner membrane ABC-transporter, Irp6 TR:Q9X9I5 (EMBL:AJ132668) (600 aa) fasta scores: E(): 0, 30.8% id in 582 aa, and to Yersinia pestis hypothetical protein YbtQ TR:Q9Z375 (EMBL:AL031866) (600 aa) fasta scores: E(): 0, 33.7% id in 594 aa.
  
    0.786
YPO0771
ABC-transporter transmembrane protein; Similar to Yersinia enterocolitica,high-pathogenicity island, lipoprotein inner membrane ABC-transporter, Irp6 TR:Q9X9I5 (EMBL:AJ132668) (600 aa) fasta scores: E(): 0, 32.4% id in 574 aa, and to Yersinia pestis hypothetical protein protein YbtP TR:Q9R7V3 (EMBL:AL031866) (600 aa) fasta scores: E(): 0, 32.6% id in 574 aa.
  
    0.786
YPO0775
Conserved hypothetical protein; Similar to Corynebacterium diphtheriae DtxR/iron-regulated protein 2 Irp2 TR:Q46024 (EMBL:U02634) (369 aa) fasta scores: E(): 2.2e-06, 23.3% id in 339 aa. N-terminal region similar to N-terminus of Pseudomonas aeruginosa hypothetical protein PA4362 TR:AAG07750 (EMBL:AE004852) (352 aa) fasta scores: E(): 0.054, 27.8% id in 209 aa.
  
    0.774
irp5
Previously sequenced: Yersinia pestis yersiniabactin siderophore biosynthetic protein YbtE TR:Q56950 (EMBL:U50364) (525 aa) fasta scores: E(): 0, 100.0% id in 525 aa. Similar to Yersinia enterocolitica Irp5 protein TR:O54514 (EMBL:Y12527) (525 aa) fasta scores: E(): 0,97.9% id in 525 aa.
 
    0.745
YPO0778
Putative siderophore biosysnthesis protein; Similar to Yersinia pestis yersiniabactin biogenesis protein Irp2 TR:Q9Z399 (EMBL:AL031866) (2041 aa) fasta scores: E(): 0, 36.8% id in 2031 aa, and to C-terminus of Stigmatella aurantiaca myxothiazol biosynthetic protein MtaD TR:Q9RFK8 (EMBL:AF188287) (3291 aa) fasta scores: E(): 0, 32.0% id in 1435 aa.
 
    0.678
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
Server load: medium (72%) [HD]