STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aasAas bifunctional protein; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1. (718 aa)    
Predicted Functional Partners:
irp1
Previously sequenced as Yersinia pestis yersiniabactin biosynthetic protein Irp1 TR:Q9Z373 (EMBL:AL031866) (3163 aa) fasta scores: E(): 0, 100.0% id in 3163 aa. Similar to Yersinia enterocolitica HMWP1 protein Irp1 TR:O54511 (EMBL:Y12527) (3161 aa) fasta scores: E(): 0, 97.9% id in 3163 aa.
  
 0.999
ygeD
Putative membrane protein; Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell; Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
 
 0.989
pldB
Similar to Escherichia coli lysophospholipase L2 PldB SW:PLDB_ECOLI (P07000) (340 aa) fasta scores: E(): 0,60.4% id in 333 aa, and to Salmonella typhimurium LT2 lysophospholipase PldB TR:Q9L6N5 (EMBL:AF233324) (338 aa) fasta scores: E(): 0, 57.4% id in 333 aa.
  
 0.969
pldA
Phospholipase A; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family.
   
 
 0.956
psd
Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
    
 0.955
pss
Similar to Escherichia coli CDP-diacylglycerol--serine O-phosphatidyltransferase PssA or Pss SW:PSS_ECOLI (P23830) (451 aa) fasta scores: E(): 0,74.1% id in 451 aa, and to Haemophilus influenzae CDP-diacylglycerol--serine O-phosphatidyltransferase PssA or Hi0425 SW:PSS_HAEIN (P44704) (455 aa) fasta scores: E(): 0, 50.1% id in 457 aa.
  
 
 0.947
YPO1462
Similar to Escherichia coli acyl carrier protein AcpP SW:ACP_ECOLI (P02901) (77 aa) fasta scores: E(): 0.12,33.3% id in 63 aa, and to Vibrio marinus acyl carrier protein AcpP TR:Q9RA32 (EMBL:AB021978) (78 aa) fasta scores: E(): 0.0026, 38.4% id in 73 aa.
  
 0.938
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 0.938
ynbD
Putative dual specificity phosphatase; Similar to Escherichia coli hypothetical protein YnbD SW:YNBD_ECOLI (P76093) (430 aa) fasta scores: E(): 0,49.6% id in 415 aa, and to Pseudomonas aeruginosa hypothetical protein PA2539 TR:AAG05927 (EMBL:AE004681) (437 aa) fasta scores: E(): 0, 44.0% id in 432 aa.
 
 0.933
irp2
Previously sequenced as Yersinia pestis yersiniabactin biosynthetic protein Irp2 TR:Q9Z399 (EMBL:AL031866) (2041 aa) fasta scores: E(): 0, 100.0% id in 2035 aa. Similar to Yersinia enterocolitica high-molecular-weight protein 2 Irp2 SW:HMP2_YEREN (P48633) (2035 aa) fasta scores: E(): 0, 98.6% id in 2035 aa. The previously sequenced Yersinia pestis Irp2 ORF starts at a valine situated 6 aa upstream from the methionine. However,the methionine start, has a good ribosome-binding site.
  
 0.921
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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