STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YPO0950Similar to Escherichia coli hypothetical protein YggL SW:YGGL_ECOLI (P38521) (108 aa) fasta scores: E(): 0,78.7% id in 108 aa, and to Haemophilus influenzae hypothetical protein HI0341 SW:YGGL_HAEIN (P44649) (114 aa) fasta scores: E(): 1.7e-27, 59.3% id in 108 aa. (108 aa)    
Predicted Functional Partners:
trmB
Putative methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
  
    0.836
pss
Similar to Escherichia coli CDP-diacylglycerol--serine O-phosphatidyltransferase PssA or Pss SW:PSS_ECOLI (P23830) (451 aa) fasta scores: E(): 0,74.1% id in 451 aa, and to Haemophilus influenzae CDP-diacylglycerol--serine O-phosphatidyltransferase PssA or Hi0425 SW:PSS_HAEIN (P44704) (455 aa) fasta scores: E(): 0, 50.1% id in 457 aa.
  
     0.615
rtrY
Putative Trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity); Belongs to the TrpR family.
  
    0.610
YPO0013a
Conserved hypothetical protein; Similar to Pectobacterium carotovorum subsp. cartovorum hypothetical protein YihD TR:Q9RB12 (EMBL:AF146615) (89 aa) fasta scores: E(): 6.2e-31, 83.1% id in 89 aa and to Escherichia coli hypothetical protein YihD SW:YIHD_ECOLI (P32126) (89 aa) fasta scores: E(): 1.7e-28, 76.4% id in 89 aa.
  
     0.609
YPO2038
Similar to Escherichia coli hypothetical protein YcdY SW:YCDY_ECOLI (P75915) (184 aa) fasta scores: E(): 0,65.9% id in 182 aa, and to Haemophilus influenzae hypothetical protein HI1543 SW:YCDY_HAEIN (P44248) (184 aa) fasta scores: E(): 7.3e-18, 42.0% id in 188 aa.
  
    0.597
lapA
Putative membrane protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
    0.573
pyrI
Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase.
   
    0.573
glsA1
Similar to Escherichia coli hypothetical protein YggN SW:YGGN_ECOLI (P46143) (239 aa) fasta scores: E(): 0,60.6% id in 231 aa, and to Vibrio cholerae hypothetical protein VC2286 TR:Q9KPS6 (EMBL:AE004299) (256 aa) fasta scores: E(): 0.00045, 26.1% id in 241 aa. Contains a frameshift after codon 166. Frame shift occurs at a poly A pentamer. The sequence has been checked and is believed to be correct; Belongs to the glutaminase family.
  
    0.556
YPO1262
Similar to Escherichia coli nucleoid-associated protein YejK SW:NA37_ECOLI (P33920) (334 aa) fasta scores: E(): 0, 79.7% id in 330 aa, and to Vibrio cholerae hypothetical protein VC2039 TR:Q9KQF9 (EMBL:AE004278) (333 aa) fasta scores: E(): 0, 54.4% id in 331 aa.
  
    0.547
matP
Conserved hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
  
     0.544
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.