node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
YPO0970 | clpB3 | YPO0970 | YPO0971 | Similar to Pseudomonas aeruginosa conserved hypothetical protein TR:AAG03485 (EMBL:AE004448) (741 aa) fasta scores: E(): 3.9e-22, 24.1% id in 771 aa, and to the N-terminal region of Escherichia coli hypothetical protein VgrE TR:O52660 (EMBL:AF044499) (702 aa) fasta scores: E(): 1.5e-19, 22.1% id in 721 aa. Similar to YPO1472 (94.6% identity in 782 aa overlap), YPO0962 (87.2% identity in 211 aa overlap) and YPO0967 (90.0% identity in 211 aa overlap). | Clp ATPase; Similar to Escherichia coli ClpB protein, which is thought to form part of a multi-chaperone system supressing protein aggregation, SW:CLPB_ECOLI (P03815) (857 aa) fasta scores: E(): 0, 39.4% identity in 872 aa overlap and Yersinia enterocolitica Clp protease-associated protein ClpB TR:AAG00524 (EMBL:AF285784) (890 aa) fasta scores: E(): 0, 43.2% id in 876 aa. Similar to YPO1471 (95.0% identity in 879 aa overlap); Belongs to the ClpA/ClpB family. | 0.850 |
YPO2840 | barA | YPO2840 | YPO3381 | Putative heat shock protein; Similarity to an internal region of Methanosarcina thermophila heat shock protein 70 Hsp70 TR:Q9UXR0 (EMBL:Y17862) (610 aa) fasta scores: E(): 1.6e-06, 25.3% id in 359 aa. Full length CDS is similar to Escherichia coli hypothetical protein YegD SW:YEGD_ECOLI (P36928) (450 aa) fasta scores: E(): 0, 71.8% id in 450 aa. | Two-component regulatory protein; Similar to Escherichia coli sensor protein BarA SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 61.6% id in 928 aa, and to Erwinia carotovora subsp. carotovora sensor/regulator protein RpfA TR:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 59.7% id in 938 aa. | 0.469 |
YPO2840 | clpB3 | YPO2840 | YPO0971 | Putative heat shock protein; Similarity to an internal region of Methanosarcina thermophila heat shock protein 70 Hsp70 TR:Q9UXR0 (EMBL:Y17862) (610 aa) fasta scores: E(): 1.6e-06, 25.3% id in 359 aa. Full length CDS is similar to Escherichia coli hypothetical protein YegD SW:YEGD_ECOLI (P36928) (450 aa) fasta scores: E(): 0, 71.8% id in 450 aa. | Clp ATPase; Similar to Escherichia coli ClpB protein, which is thought to form part of a multi-chaperone system supressing protein aggregation, SW:CLPB_ECOLI (P03815) (857 aa) fasta scores: E(): 0, 39.4% identity in 872 aa overlap and Yersinia enterocolitica Clp protease-associated protein ClpB TR:AAG00524 (EMBL:AF285784) (890 aa) fasta scores: E(): 0, 43.2% id in 876 aa. Similar to YPO1471 (95.0% identity in 879 aa overlap); Belongs to the ClpA/ClpB family. | 0.876 |
YPO2840 | clpP | YPO2840 | YPO3157 | Putative heat shock protein; Similarity to an internal region of Methanosarcina thermophila heat shock protein 70 Hsp70 TR:Q9UXR0 (EMBL:Y17862) (610 aa) fasta scores: E(): 1.6e-06, 25.3% id in 359 aa. Full length CDS is similar to Escherichia coli hypothetical protein YegD SW:YEGD_ECOLI (P36928) (450 aa) fasta scores: E(): 0, 71.8% id in 450 aa. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.760 |
YPO2840 | dnaJ | YPO2840 | YPO0469 | Putative heat shock protein; Similarity to an internal region of Methanosarcina thermophila heat shock protein 70 Hsp70 TR:Q9UXR0 (EMBL:Y17862) (610 aa) fasta scores: E(): 1.6e-06, 25.3% id in 359 aa. Full length CDS is similar to Escherichia coli hypothetical protein YegD SW:YEGD_ECOLI (P36928) (450 aa) fasta scores: E(): 0, 71.8% id in 450 aa. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.992 |
YPO2840 | grpE | YPO2840 | YPO1107 | Putative heat shock protein; Similarity to an internal region of Methanosarcina thermophila heat shock protein 70 Hsp70 TR:Q9UXR0 (EMBL:Y17862) (610 aa) fasta scores: E(): 1.6e-06, 25.3% id in 359 aa. Full length CDS is similar to Escherichia coli hypothetical protein YegD SW:YEGD_ECOLI (P36928) (450 aa) fasta scores: E(): 0, 71.8% id in 450 aa. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.979 |
YPO2840 | infB | YPO2840 | YPO3496 | Putative heat shock protein; Similarity to an internal region of Methanosarcina thermophila heat shock protein 70 Hsp70 TR:Q9UXR0 (EMBL:Y17862) (610 aa) fasta scores: E(): 1.6e-06, 25.3% id in 359 aa. Full length CDS is similar to Escherichia coli hypothetical protein YegD SW:YEGD_ECOLI (P36928) (450 aa) fasta scores: E(): 0, 71.8% id in 450 aa. | Translation initiation factor IF2-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.512 |
barA | YPO2840 | YPO3381 | YPO2840 | Two-component regulatory protein; Similar to Escherichia coli sensor protein BarA SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 61.6% id in 928 aa, and to Erwinia carotovora subsp. carotovora sensor/regulator protein RpfA TR:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 59.7% id in 938 aa. | Putative heat shock protein; Similarity to an internal region of Methanosarcina thermophila heat shock protein 70 Hsp70 TR:Q9UXR0 (EMBL:Y17862) (610 aa) fasta scores: E(): 1.6e-06, 25.3% id in 359 aa. Full length CDS is similar to Escherichia coli hypothetical protein YegD SW:YEGD_ECOLI (P36928) (450 aa) fasta scores: E(): 0, 71.8% id in 450 aa. | 0.469 |
barA | clpB3 | YPO3381 | YPO0971 | Two-component regulatory protein; Similar to Escherichia coli sensor protein BarA SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 61.6% id in 928 aa, and to Erwinia carotovora subsp. carotovora sensor/regulator protein RpfA TR:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 59.7% id in 938 aa. | Clp ATPase; Similar to Escherichia coli ClpB protein, which is thought to form part of a multi-chaperone system supressing protein aggregation, SW:CLPB_ECOLI (P03815) (857 aa) fasta scores: E(): 0, 39.4% identity in 872 aa overlap and Yersinia enterocolitica Clp protease-associated protein ClpB TR:AAG00524 (EMBL:AF285784) (890 aa) fasta scores: E(): 0, 43.2% id in 876 aa. Similar to YPO1471 (95.0% identity in 879 aa overlap); Belongs to the ClpA/ClpB family. | 0.803 |
barA | clpP | YPO3381 | YPO3157 | Two-component regulatory protein; Similar to Escherichia coli sensor protein BarA SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 61.6% id in 928 aa, and to Erwinia carotovora subsp. carotovora sensor/regulator protein RpfA TR:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 59.7% id in 938 aa. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.409 |
barA | dnaJ | YPO3381 | YPO0469 | Two-component regulatory protein; Similar to Escherichia coli sensor protein BarA SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 61.6% id in 928 aa, and to Erwinia carotovora subsp. carotovora sensor/regulator protein RpfA TR:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 59.7% id in 938 aa. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.781 |
barA | dnaK | YPO3381 | YPO0468 | Two-component regulatory protein; Similar to Escherichia coli sensor protein BarA SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 61.6% id in 928 aa, and to Erwinia carotovora subsp. carotovora sensor/regulator protein RpfA TR:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 59.7% id in 938 aa. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.469 |
barA | hsc | YPO3381 | YPO2892 | Two-component regulatory protein; Similar to Escherichia coli sensor protein BarA SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 61.6% id in 928 aa, and to Erwinia carotovora subsp. carotovora sensor/regulator protein RpfA TR:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 59.7% id in 938 aa. | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU (By similarity). | 0.469 |
clpB3 | YPO0970 | YPO0971 | YPO0970 | Clp ATPase; Similar to Escherichia coli ClpB protein, which is thought to form part of a multi-chaperone system supressing protein aggregation, SW:CLPB_ECOLI (P03815) (857 aa) fasta scores: E(): 0, 39.4% identity in 872 aa overlap and Yersinia enterocolitica Clp protease-associated protein ClpB TR:AAG00524 (EMBL:AF285784) (890 aa) fasta scores: E(): 0, 43.2% id in 876 aa. Similar to YPO1471 (95.0% identity in 879 aa overlap); Belongs to the ClpA/ClpB family. | Similar to Pseudomonas aeruginosa conserved hypothetical protein TR:AAG03485 (EMBL:AE004448) (741 aa) fasta scores: E(): 3.9e-22, 24.1% id in 771 aa, and to the N-terminal region of Escherichia coli hypothetical protein VgrE TR:O52660 (EMBL:AF044499) (702 aa) fasta scores: E(): 1.5e-19, 22.1% id in 721 aa. Similar to YPO1472 (94.6% identity in 782 aa overlap), YPO0962 (87.2% identity in 211 aa overlap) and YPO0967 (90.0% identity in 211 aa overlap). | 0.850 |
clpB3 | YPO2840 | YPO0971 | YPO2840 | Clp ATPase; Similar to Escherichia coli ClpB protein, which is thought to form part of a multi-chaperone system supressing protein aggregation, SW:CLPB_ECOLI (P03815) (857 aa) fasta scores: E(): 0, 39.4% identity in 872 aa overlap and Yersinia enterocolitica Clp protease-associated protein ClpB TR:AAG00524 (EMBL:AF285784) (890 aa) fasta scores: E(): 0, 43.2% id in 876 aa. Similar to YPO1471 (95.0% identity in 879 aa overlap); Belongs to the ClpA/ClpB family. | Putative heat shock protein; Similarity to an internal region of Methanosarcina thermophila heat shock protein 70 Hsp70 TR:Q9UXR0 (EMBL:Y17862) (610 aa) fasta scores: E(): 1.6e-06, 25.3% id in 359 aa. Full length CDS is similar to Escherichia coli hypothetical protein YegD SW:YEGD_ECOLI (P36928) (450 aa) fasta scores: E(): 0, 71.8% id in 450 aa. | 0.876 |
clpB3 | barA | YPO0971 | YPO3381 | Clp ATPase; Similar to Escherichia coli ClpB protein, which is thought to form part of a multi-chaperone system supressing protein aggregation, SW:CLPB_ECOLI (P03815) (857 aa) fasta scores: E(): 0, 39.4% identity in 872 aa overlap and Yersinia enterocolitica Clp protease-associated protein ClpB TR:AAG00524 (EMBL:AF285784) (890 aa) fasta scores: E(): 0, 43.2% id in 876 aa. Similar to YPO1471 (95.0% identity in 879 aa overlap); Belongs to the ClpA/ClpB family. | Two-component regulatory protein; Similar to Escherichia coli sensor protein BarA SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 61.6% id in 928 aa, and to Erwinia carotovora subsp. carotovora sensor/regulator protein RpfA TR:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 59.7% id in 938 aa. | 0.803 |
clpB3 | clpP | YPO0971 | YPO3157 | Clp ATPase; Similar to Escherichia coli ClpB protein, which is thought to form part of a multi-chaperone system supressing protein aggregation, SW:CLPB_ECOLI (P03815) (857 aa) fasta scores: E(): 0, 39.4% identity in 872 aa overlap and Yersinia enterocolitica Clp protease-associated protein ClpB TR:AAG00524 (EMBL:AF285784) (890 aa) fasta scores: E(): 0, 43.2% id in 876 aa. Similar to YPO1471 (95.0% identity in 879 aa overlap); Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.924 |
clpB3 | clpS | YPO0971 | YPO1367 | Clp ATPase; Similar to Escherichia coli ClpB protein, which is thought to form part of a multi-chaperone system supressing protein aggregation, SW:CLPB_ECOLI (P03815) (857 aa) fasta scores: E(): 0, 39.4% identity in 872 aa overlap and Yersinia enterocolitica Clp protease-associated protein ClpB TR:AAG00524 (EMBL:AF285784) (890 aa) fasta scores: E(): 0, 43.2% id in 876 aa. Similar to YPO1471 (95.0% identity in 879 aa overlap); Belongs to the ClpA/ClpB family. | Conserved hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.810 |
clpB3 | dnaJ | YPO0971 | YPO0469 | Clp ATPase; Similar to Escherichia coli ClpB protein, which is thought to form part of a multi-chaperone system supressing protein aggregation, SW:CLPB_ECOLI (P03815) (857 aa) fasta scores: E(): 0, 39.4% identity in 872 aa overlap and Yersinia enterocolitica Clp protease-associated protein ClpB TR:AAG00524 (EMBL:AF285784) (890 aa) fasta scores: E(): 0, 43.2% id in 876 aa. Similar to YPO1471 (95.0% identity in 879 aa overlap); Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.866 |
clpB3 | dnaK | YPO0971 | YPO0468 | Clp ATPase; Similar to Escherichia coli ClpB protein, which is thought to form part of a multi-chaperone system supressing protein aggregation, SW:CLPB_ECOLI (P03815) (857 aa) fasta scores: E(): 0, 39.4% identity in 872 aa overlap and Yersinia enterocolitica Clp protease-associated protein ClpB TR:AAG00524 (EMBL:AF285784) (890 aa) fasta scores: E(): 0, 43.2% id in 876 aa. Similar to YPO1471 (95.0% identity in 879 aa overlap); Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.939 |