Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
YPO0976Similar to Vibrio cholerae hypothetical protein VCA0114 TR:Q9KN51 (EMBL:AE004353) (444 aa) fasta scores: E(): 6.8e-31, 27.8% id in 449 aa, and to Pseudomonas aeruginosa hypothetical protein PA0079 TR:AAG03469 (EMBL:AE004447) (444 aa) fasta scores: E(): 6.6e-30, 28.7% id in 449 aa. Almost identical to YPO1467 (98.9% identity in 450 aa overlap). (450 aa)    
Predicted Functional Partners:
YPO0978
Similar to Vibrio cholerae hypothetical protein VCA0107 TR:Q9KN58 (EMBL:AE004353) (168 aa) fasta scores: E(): 9.8e-18, 41.0% id in 156 aa, and to Pseudomonas aeruginosa conserved hypothetical protein PA1657 TR:AAG05046 (EMBL:AE004593) (168 aa) fasta scores: E(): 1.2e-18, 39.2% id in 158 aa. Almost identical to YPO1465 (97.6% identity in 166 aa overlap).
 
 
 0.963
YPO0977
Conserved hypothetical protein; Similar to the C-terminal regions of Vibrio cholerae hypothetical protein VCA0108 TR:Q9KN57 (EMBL:AE004353) (492 aa) fasta scores: E(): 0, 43.4% id in 488 aa, and Pseudomonas aeruginosa conserved hypothetical protein PA1658 TR:AAG05047 (EMBL:AE004593) (491 aa) fasta scores: E(): 0, 43.3% id in 450 aa. Almost identical to YPO1466 (98.8% identity in 516 aa overlap).
 
 
 0.959
YPO0975
Putative membrane protein; Similar to Vibrio cholerae hypothetical protein VCA0115 TR:Q9KN50 (EMBL:AE004353) (257 aa) fasta scores: E(): 3.1e-05, 25.2% id in 206 aa. Identical to YPO1468.
 
  
 0.954
YPO0973
Conserved hypothetical protein; Similar to Vibrio cholerae secreted hydrophilic protein VC1415 TR:P72350 (EMBL:S81006) (172 aa) fasta scores: E(): 3.9e-18, 37.8% id in 143 aa, and to Pseudomonas aeruginosa probable secreted protein HcpC TR:AAG03652 (EMBL:AE004464) (172 aa) fasta scores: E(): 1.6e-17, 35.5% id in 166 aa. Identical to YPO1470.
 
 
  0.944
YPO0974
Putative OmpA-family membrane protein; No significant database matches to the full length CDS. Similar to C-terminus of Pseudomonas fluorescens major outer-membrane protein OprF TR:Q51780 (EMBL:L21200) (317 aa) fasta scores: E(): 2.2e-08, 37.1% id in 159 aa. Almost identical to YPO1469 (99.5% identity in 578 aa overlap).
 
  
  0.920
YPO3707
Similar to Escherichia coli hypothetical protein 498 TR:O52670 (EMBL:AF044503) (166 aa) fasta scores: E(): 0,62.0% id in 166 aa, and to Vibrio cholerae hypothetical protein VCA0107 TR:Q9KN58 (EMBL:AE004353) (168 aa) fasta scores: E(): 0, 61.3% id in 160 aa.
 
 
 0.910
YPO1465
Similar to Pseudomonas aeruginosa hypothetical protein PA1657 TR:AAG05046 (EMBL:AE004593) (168 aa) fasta scores: E(): 1.3e-18, 39.2% id in 158 aa, and to Vibrio cholerae hypothetical protein VCA0107 TR:Q9KN58 (EMBL:AE004353) (168 aa) fasta scores: E(): 2.7e-18, 41.0% id in 156 aa. Highly similar to YPO0978 (97.6% identity in 166 aa overlap).
 
 
 0.904
YPO0500
Similar to Pseudomonas aeruginosa hypothetical protein PA0083 TR:AAG03473 (EMBL:AE004447) (172 aa) fasta scores: E(): 0, 59.9% id in 162 aa, and to Edwardsiella ictaluri putative protein EIP20 TR:O52407 (EMBL:AF037441) (170 aa) fasta scores: E(): 2.1e-20, 41.1% id in 163 aa. Similar to YPO2939 (59.3% identity in 162 aa overlap).
 
 
 0.879
YPO2939
Similar to Pseudomonas aeruginosa hypothetical protein PA0083 TR:AAG03473 (EMBL:AE004447) (172 aa) fasta scores: E(): 0, 73.6% id in 174 aa, and to Edwardsiella ictaluri hypothetical protein Eip20 TR:O52407 (EMBL:AF037441) (170 aa) fasta scores: E(): 5e-21, 42.5% id in 160 aa. Similar to YPO0500 (59.3% identity in 162 aa overlap).
 
 
 0.865
YPO1466
Similar to Vibrio cholerae hypothetical protein VCA0108 TR:Q9KN57 (EMBL:AE004353) (492 aa) fasta scores: E(): 0, 43.9% id in 488 aa, and to Pseudomonas aeruginosa hypothetical protein PA1658 TR:AAG05047 (EMBL:AE004593) (491 aa) fasta scores: E(): 0, 44.0% id in 450 aa. CDS contains sequence divergence at the N-terminus. Highly similar to YPO0977 (98.8% identity in 516 aa overlap).
 
 
 0.835
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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