| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| b0728 | b4152 | YPO1115 | YPO0358 | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Fumarate reductase hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | 0.951 |
| b0728 | b4153 | YPO1115 | YPO0359 | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Similar to Escherichia coli fumarate reductase iron-sulfur protein FrdB SW:FRDB_ECOLI (P00364) (243 aa) fasta scores: E(): 0, 85.5% id in 242 aa; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.996 |
| b0728 | cybA | YPO1115 | YPO1109 | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Similar to Escherichia coli succinate dehydrogenase cytochrome b556 subunit SdhC SW:DHSC_ECOLI (P10446) (129 aa) fasta scores: E(): 0, 77.2% id in 127 aa, and to Vibrio cholerae succinate dehydrogenase, cytochrome b556 subunit VC2091 TR:Q9KQA9 (EMBL:AE004283) (130 aa) fasta scores: E(): 0, 75.0% id in 124 aa. | 0.998 |
| b0728 | fumA | YPO1115 | YPO3335 | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.935 |
| b0728 | fumC | YPO1115 | YPO2264 | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.874 |
| b0728 | nifJ | YPO1115 | YPO2334 | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Similar to Escherichia coli probable pyruvate-flavodoxin oxidoreductase YdbK SW:NIFJ_ECOLI (P52647) (1174 aa) fasta scores: E(): 0, 80.5% id in 1177 aa, and to Klebsiella pneumoniae pyruvate-flavodoxin oxidoreductase NifJ SW:NIFJ_KLEPN (P03833) (1171 aa) fasta scores: E(): 0, 48.0% id in 1184 aa. | 0.979 |
| b0728 | sdhA | YPO1115 | YPO1111 | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Similar to Escherichia coli succinate dehydrogenase flavoprotein subunit SdhA SW:DHSA_ECOLI (P10444) (588 aa) fasta scores: E(): 0, 92.0% id in 588 aa, and to Vibrio cholerae succinate dehydrogenase, flavoprotein subunit VC2089 TR:Q9KQB1 (EMBL:AE004283) (588 aa) fasta scores: E(): 0, 82.3% id in 588 aa; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.997 |
| b0728 | sdhB | YPO1115 | YPO1112 | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Similar to Escherichia coli succinate dehydrogenase iron-sulfur protein SdhB SW:DHSB_ECOLI (P07014) (238 aa) fasta scores: E(): 0, 90.8% id in 238 aa, and to Vibrio cholerae succinate dehydrogenase, iron-sulfur protein VC2088 TR:Q9KQB2 (EMBL:AE004283) (236 aa) fasta scores: E(): 0, 80.2% id in 237 aa; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.999 |
| b0728 | sdhD | YPO1115 | YPO1110 | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.998 |
| b0728 | sucD | YPO1115 | YPO1116 | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.999 |
| b4152 | b0728 | YPO0358 | YPO1115 | Fumarate reductase hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.951 |
| b4152 | b4153 | YPO0358 | YPO0359 | Fumarate reductase hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | Similar to Escherichia coli fumarate reductase iron-sulfur protein FrdB SW:FRDB_ECOLI (P00364) (243 aa) fasta scores: E(): 0, 85.5% id in 242 aa; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.999 |
| b4152 | cybA | YPO0358 | YPO1109 | Fumarate reductase hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | Similar to Escherichia coli succinate dehydrogenase cytochrome b556 subunit SdhC SW:DHSC_ECOLI (P10446) (129 aa) fasta scores: E(): 0, 77.2% id in 127 aa, and to Vibrio cholerae succinate dehydrogenase, cytochrome b556 subunit VC2091 TR:Q9KQA9 (EMBL:AE004283) (130 aa) fasta scores: E(): 0, 75.0% id in 124 aa. | 0.912 |
| b4152 | fumA | YPO0358 | YPO3335 | Fumarate reductase hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.960 |
| b4152 | fumC | YPO0358 | YPO2264 | Fumarate reductase hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.959 |
| b4152 | sdhA | YPO0358 | YPO1111 | Fumarate reductase hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | Similar to Escherichia coli succinate dehydrogenase flavoprotein subunit SdhA SW:DHSA_ECOLI (P10444) (588 aa) fasta scores: E(): 0, 92.0% id in 588 aa, and to Vibrio cholerae succinate dehydrogenase, flavoprotein subunit VC2089 TR:Q9KQB1 (EMBL:AE004283) (588 aa) fasta scores: E(): 0, 82.3% id in 588 aa; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.993 |
| b4152 | sdhB | YPO0358 | YPO1112 | Fumarate reductase hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | Similar to Escherichia coli succinate dehydrogenase iron-sulfur protein SdhB SW:DHSB_ECOLI (P07014) (238 aa) fasta scores: E(): 0, 90.8% id in 238 aa, and to Vibrio cholerae succinate dehydrogenase, iron-sulfur protein VC2088 TR:Q9KQB2 (EMBL:AE004283) (236 aa) fasta scores: E(): 0, 80.2% id in 237 aa; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.993 |
| b4152 | sdhD | YPO0358 | YPO1110 | Fumarate reductase hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.913 |
| b4152 | sucD | YPO0358 | YPO1116 | Fumarate reductase hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.946 |
| b4153 | b0728 | YPO0359 | YPO1115 | Similar to Escherichia coli fumarate reductase iron-sulfur protein FrdB SW:FRDB_ECOLI (P00364) (243 aa) fasta scores: E(): 0, 85.5% id in 242 aa; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.996 |