Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
adiCPutative amino acid permease; Major component of the acid-resistance (AR) system allowing enteric pathogens to survive the acidic environment in the stomach. Exchanges extracellular arginine for its intracellular decarboxylation product agmatine (Agm) thereby expelling intracellular protons (By similarity); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family. (444 aa)    
Predicted Functional Partners:
YPO1201
Putative amino acid decarboxylase; Similar to Escherichia coli biodegradative arginine decarboxylase AdiA or Adi SW:ADIA_ECOLI (P28629) (755 aa) fasta scores: E(): 0, 52.4% id in 757 aa, and to Vibrio cholerae ornithine decarboxylase, inducible VCA1063 TR:Q9KKN9 (EMBL:AE004431) (720 aa) fasta scores: E(): 0,34.0% id in 633 aa.
 
  
 0.774
ccmG
Thiol:disulfide interchange protein DsbE; Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase (By similarity); Belongs to the thioredoxin family. DsbE subfamily.
    
 0.646
speC
Ornithine decarboxylase; Similar to Escherichia coli constitutive ornithine decarboxylase SpeC SW:DCOR_ECOLI (P21169) (731 aa) fasta scores: E(): 0, 73.1% id in 718 aa, and to Vibrio cholerae inducible ornithine decarboxylase VCA1063 TR:Q9KKN9 (EMBL:AE004431) (720 aa) fasta scores: E(): 0, 72.4% id in 718 aa.
 
  
 0.637
olgH
Similar to Escherichia coli trehalose-6-phosphate hydrolase TreC or OlgH SW:TREC_ECOLI (P28904) (551 aa) fasta scores: E(): 0, 74.0% id in 547 aa, and to Vibrio cholerae trehalose-6-phosphate hydrolase Vc0911 TR:Q9KTJ1 (EMBL:AE004175) (562 aa) fasta scores: E(): 0, 60.9% id in 550 aa.
  
 
  0.610
malZ
Similar to Escherichia coli maltodextrin glucosidase MalZ SW:MALZ_ECOLI (P21517) (605 aa) fasta scores: E(): 0,57.7% id in 608 aa; Belongs to the glycosyl hydrolase 13 family.
  
 
  0.595
YPO0682
MotA/TolQ/ExbB proton channel family protein; Similar to Escherichia coli biopolymer transport protein ExbB SW:EXBB_ECOLI (P18783) (244 aa) fasta scores: E(): 0, 70.8% id in 236 aa, and to Pseudomonas putida biopolymer transport protein ExbB SW:EXBB_PSEPU (Q05605) (329 aa) fasta scores: E(): 0, 62.7% id in 236 aa.
  
   
 0.578
irp1
Previously sequenced as Yersinia pestis yersiniabactin biosynthetic protein Irp1 TR:Q9Z373 (EMBL:AL031866) (3163 aa) fasta scores: E(): 0, 100.0% id in 3163 aa. Similar to Yersinia enterocolitica HMWP1 protein Irp1 TR:O54511 (EMBL:Y12527) (3161 aa) fasta scores: E(): 0, 97.9% id in 3163 aa.
  
 0.578
malS
Similar to Escherichia coli alpha-amylase protein MalS SW:AMY1_ECOLI (P25718) (676 aa) fasta scores: E(): 0,70.1% id in 680 aa, and to Klebsiella pneumoniae maltohexaose-producing amylase TR:Q9RHR1 (EMBL:AB026834) (677 aa) fasta scores: E(): 0, 68.9% id in 687 aa.
    
  0.544
adgA
Putative glutamine-dependent NAD; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
 0.527
motB
Similar to Escherichia coli chemotaxis MotB protein SW:MOTB_ECOLI (P09349) (308 aa) fasta scores: E(): 0, 68.8% id in 311 aa, and to Salmonella typhimurium chemotaxis MotB protein SW:MOTB_SALTY (P55892) (309 aa) fasta scores: E(): 0, 67.9% id in 312 aa. Note that this CDS is 119 aa longer,at the C-terminal end, than the MotB protein.
      
 0.516
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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