STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adiCPutative amino acid permease; Major component of the acid-resistance (AR) system allowing enteric pathogens to survive the acidic environment in the stomach. Exchanges extracellular arginine for its intracellular decarboxylation product agmatine (Agm) thereby expelling intracellular protons (By similarity); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family. (444 aa)    
Predicted Functional Partners:
olgH
Similar to Escherichia coli trehalose-6-phosphate hydrolase TreC or OlgH SW:TREC_ECOLI (P28904) (551 aa) fasta scores: E(): 0, 74.0% id in 547 aa, and to Vibrio cholerae trehalose-6-phosphate hydrolase Vc0911 TR:Q9KTJ1 (EMBL:AE004175) (562 aa) fasta scores: E(): 0, 60.9% id in 550 aa.
  
 0.846
malZ
Similar to Escherichia coli maltodextrin glucosidase MalZ SW:MALZ_ECOLI (P21517) (605 aa) fasta scores: E(): 0,57.7% id in 608 aa; Belongs to the glycosyl hydrolase 13 family.
  
 0.842
malS
Similar to Escherichia coli alpha-amylase protein MalS SW:AMY1_ECOLI (P25718) (676 aa) fasta scores: E(): 0,70.1% id in 680 aa, and to Klebsiella pneumoniae maltohexaose-producing amylase TR:Q9RHR1 (EMBL:AB026834) (677 aa) fasta scores: E(): 0, 68.9% id in 687 aa.
   
 0.834
YPO1201
Putative amino acid decarboxylase; Similar to Escherichia coli biodegradative arginine decarboxylase AdiA or Adi SW:ADIA_ECOLI (P28629) (755 aa) fasta scores: E(): 0, 52.4% id in 757 aa, and to Vibrio cholerae ornithine decarboxylase, inducible VCA1063 TR:Q9KKN9 (EMBL:AE004431) (720 aa) fasta scores: E(): 0,34.0% id in 633 aa.
 
  
 0.724
adgA
Putative glutamine-dependent NAD; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.623
speC
Ornithine decarboxylase; Similar to Escherichia coli constitutive ornithine decarboxylase SpeC SW:DCOR_ECOLI (P21169) (731 aa) fasta scores: E(): 0, 73.1% id in 718 aa, and to Vibrio cholerae inducible ornithine decarboxylase VCA1063 TR:Q9KKN9 (EMBL:AE004431) (720 aa) fasta scores: E(): 0, 72.4% id in 718 aa.
 
  
 0.588
trpC
Tryptophan biosynthesis protein TrpCF; Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain (By similarity).
    
 
 0.562
irp1
Previously sequenced as Yersinia pestis yersiniabactin biosynthetic protein Irp1 TR:Q9Z373 (EMBL:AL031866) (3163 aa) fasta scores: E(): 0, 100.0% id in 3163 aa. Similar to Yersinia enterocolitica HMWP1 protein Irp1 TR:O54511 (EMBL:Y12527) (3161 aa) fasta scores: E(): 0, 97.9% id in 3163 aa.
  
 0.559
YPO0682
MotA/TolQ/ExbB proton channel family protein; Similar to Escherichia coli biopolymer transport protein ExbB SW:EXBB_ECOLI (P18783) (244 aa) fasta scores: E(): 0, 70.8% id in 236 aa, and to Pseudomonas putida biopolymer transport protein ExbB SW:EXBB_PSEPU (Q05605) (329 aa) fasta scores: E(): 0, 62.7% id in 236 aa.
  
   
 0.528
nanT
Putative sugar transporter; Catalyzes the proton-dependent transport of sialic acid. Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
  
    0.489
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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