STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
YPO1237Putative transcriptional regulatory protein; Similar to Escherichia coli hypothetical transcriptional regulator YgbI SW:YGBI_ECOLI (P52598) (265 aa) fasta scores: E(): 0, 42.2% id in 258 aa, and to Escherichia coli putative Aga operon transcriptional repressor AgaR SW:AGAR_ECOLI (P42902) (269 aa) fasta scores: E(): 2.7e-21, 29.8% id in 255 aa. (271 aa)    
Predicted Functional Partners:
YPO1238
Similar to hypothetical proteins from both prokaryotes and eukaryotes Escherichia coli hypothetical protein YgbM TR:AAG14983 (EMBL:AF242210) (258 aa) fasta scores: E(): 0, 42.5% id in 240 aa, and to Drosophila melanogaster transient receptor potential locus C protein precursor Gip or CG2227 SW:TRLC_DROME (P36951) (264 aa) fasta scores: E(): 1.6e-28, 38.5% id in 244 aa; Belongs to the hyi family.
 
     0.778
fpk
1-phosphofructokinase; Similar to Escherichia coli 1-phosphofructokinase FruK or Fpk SW:K1PF_ECOLI (P23539) (312 aa) fasta scores: E(): 0, 92.0% id in 312 aa, and to Haemophilus influenzae 1-phosphofructokinase FruK SW:K1PF_HAEIN (P44330) (313 aa) fasta scores: E(): 0, 55.4% id in 305 aa; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.698
yfiQ
Putative acetyltransferase; Similar to Escherichia coli hypothetical 98.0 kDa protein in ung-pssA intergenic region YfiQ SW:YFIQ_ECOLI (P76594) (886 aa) fasta scores: E(): 0, 75.5% id in 880 aa,and to Vibrio cholerae hypothetical protein Vca0574 TR:Q9KM15 (EMBL:AE004388) (893 aa) fasta scores: E(): 0,55.2% id in 889 aa, and to Entamoeba histolytica acetyl-CoA synthetase TR:Q9NAT4 (EMBL:AF286346) (713 aa) fasta scores: E(): 0, 34.0% id in 702 aa.
    
   0.679
YPO1235
Similar to Escherichia coli hypothetical protein YgbK SW:YGBK_ECOLI (Q46889) (388 aa) fasta scores: E(): 0,46.9% id in 399 aa, and to Haemophilus influenzae hypothetical protein HI1011 SW:YGBK_HAEIN (P44093) (413 aa) fasta scores: E(): 0, 48.1% id in 426 aa.
 
     0.657
fruA
Similar to Escherichia coli PTS system,fructose-specific IIBC component FruA or PtsF SW:PTFB_ECOLI (P20966) (563 aa) fasta scores: E(): 0, 77.2% id in 569 aa,and to Vibrio cholerae PTS system, fructose-specific IIBC component VCA0516 TR:Q9KM72 (EMBL:AE004382) (580 aa) fasta scores: E(): 0, 65.7% id in 531 aa.
  
  
 0.653
YPO1236
Putative class II aldolase-family protein; Similar to Escherichia coli hypothetical protein YgbL SW:YGBL_ECOLI (Q46890) (212 aa) fasta scores: E(): 0,57.1% id in 168 aa, and to Escherichia coli L-fuculose phosphate aldolase FucA or FucC or Prd SW:FUCA_ECOLI (P11550) (215 aa) fasta scores: E(): 2.6e-07, 32.7% id in 159 aa.
 
   
 0.613
YPO0405
Similar to e.g. Escherichia coli phosphoenolpyruvate-protein phosphotransferase PtsI,SW:PT1_ECOLI (P08839) (575 aa) fasta scores: E(): 0, 36.0% id in 583 aa, but has both N- and C-terminal extensions. Also similar to Escherichia coli phosphoenolpyruvate-protein phosphotransferase PtsA,SW:PT1A_ECOLI (P32670) (711 aa) fasta scores: E(): 0, 64.5% id in 726 aa and to Escherichia coli putative phosphoenolpyruvate-protein phosphotransferase YpdD,SW:YPDD_ECOLI (P77439) (831 aa) fasta scores: E(): 0, 41.5% id in 853 aa.
  
  
 0.529
YPO3312
Glycerol kinase; Similar to Bacillus subtilis glycerol kinase GlpK SW:GLPK_BACSU (P18157) (496 aa) fasta scores: E(): 0, 40.4% id in 492 aa, and to Thermotoga maritima glycerol kinase 2 GlpK2 or Tm1430 SW:GLK2_THEMA (Q9X1E4) (496 aa) fasta scores: E(): 0, 42.6% id in 491 aa.
 
  
 0.433
glpA
Similar to Escherichia coli anaerobic glycerol-3-phosphate dehydrogenase subunit A protein GlpA SW:GLPA_ECOLI (P13032) (542 aa) fasta scores: E(): 0, 77.8% id in 528 aa, and to Haemophilus influenzae anaerobic glycerol-3-phosphate dehydrogenase subunit A protein GlpA SW:GLPA_HAEIN (P43799) (563 aa) fasta scores: E(): 0, 70.5% id in 543 aa; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.416
glpD
Similar to Escherichia coli aerobic glycerol-3-phosphate dehydrogenase GlpD SW:GLPD_ECOLI (P13035) (501 aa) fasta scores: E(): 0, 75.1% id in 473 aa,and to Pseudomonas aeruginosa glycerol-3-phosphate dehydrogenase GlpD TR:AAG06972 (EMBL:L06231) (512 aa) fasta scores: E(): 0, 59.1% id in 464 aa. CDS is truncated at the N-terminus in comparison to other orthologues. Effect on function not known; was marked partial.
 
  
 0.400
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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