STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YPO1313Similar to Vibrio cholerae iron-regulated outer membrane virulence protein precursor IrgA SW:IRGA_VIBCH (P27772) (652 aa) fasta scores: E(): 0, 46.2% id in 671 aa,and to Escherichia coli exogenous ferric siderophore receptor R4 TR:O87518 (EMBL:AF081285) (669 aa) fasta scores: E(): 0, 36.9% id in 651 aa. (665 aa)    
Predicted Functional Partners:
YPO1312
Putative siderophore ABC transporter, ATP-binding subunit; Similar to Vibrio cholerae vibriobactin ABC transporter ATPase ViuC TR:Q9RCF3 (EMBL:U52150) (279 aa) fasta scores: E(): 1.5e-24, 37.7% id in 239 aa, and to Escherichia coli ferric enterobactin transport ATP-binding protein FepC SW:FEPC_ECOLI (P23878) (271 aa) fasta scores: E(): 5.2e-24, 34.1% id in 264 aa.
 
  
 0.954
tonB
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
 
 0.917
YPO3918
Putative membrane protein; Similar to Pseudomonas putida ferric-siderophore transport protein TonB SW:TONB_PSEPU (Q05613) (243 aa) fasta scores: E(): 1.5e-13, 32.0% id in 253 aa, and to Haemophilus influenzae energy transducer protein TonB SW:TONB_HAEIN (P42872) (270 aa) fasta scores: E(): 1.3e-08,27.5% id in 280 aa.
  
 
 0.859
fcuA
Similar to Yersinia enterocolitica ferrichrome receptor FcuA SW:FCUA_YEREN (Q05202) (758 aa) fasta scores: E(): 0, 83.9% id in 762 aa, and to Bordetella bronchiseptica putative ferric siderophore receptor BfrB TR:P94265 (EMBL:U77671) (734 aa) fasta scores: E(): 0,38.9% id in 730 aa.
  
 
 0.782
YPO3923
Putative TonB dependent receptor protein; Similar to C-terminal regions of Serratia marcescens HasA receptor protein HasR TR:P72473 (EMBL:Y08983) (899 aa) fasta scores: E(): 0, 55.3% id in 810 aa, and Pseudomonas fluorescens HasA receptor protein HasR TR:Q9RHT4 (EMBL:AB023289) (916 aa) fasta scores: E(): 0, 40.8% id in 830 aa.
  
 
 0.779
YPO1311
Putative FecCD-family membrane transport protein; Similar to Yersinia pestis hemin transport system permease protein HmuU SW:HMUU_YERPE (Q56992) (334 aa) fasta scores: E(): 0, 37.3% id in 335 aa, and to Corynebacterium diphtheriae ABC-type transporter permease HmuU TR:Q9XD88 (EMBL:AF109162) (350 aa) fasta scores: E(): 0, 36.3% id in 331 aa.
 
  
 0.741
YPO0339
Enhancing factor (viral); Significantly similar to many viral enhancing proteins important for the invasion of the cells of the insect midgut e.g. Pseudalatia unipuncta granulosis virus (PuGV) viral enhancing factor Vef SW:VEF_GVPU (P41723) (901 aa) fasta scores: E(): 1.5e-20, 25.2% id in 869 aa and to Lymantria dispar multicapsid nuclear polyhedrosis virus enhancin TR:O37353 (EMBL:AF019970) (782 aa) fasta scores: E(): 1.2e-24, 24.5% id in 783 aa.
    
 
 0.732
stf
Similar to Bacteriophage HK97 tail fiber Stf TR:Q9MCR6 (EMBL:AF069529) (321 aa) fasta scores: E(): 0,52.9% id in 208 aa, and to Escherichia coli DNA inversion product sc/svmR TR:Q47429 (EMBL:X62121) (760 aa) fasta scores: E(): 1.8e-28, 49.2% id in 177 aa, and to Escherichia coli side tail fiber protein homolog from lambdoid prophage S14 StfE or b1157 SW:STFE_ECOLI (P33227) (166 aa) fasta scores: E(): 1.1e-27, 49.4% id in 166 aa.
    
 
 0.732
YPO3828
Hypothetical protein; No significant database hits.
    
 
 0.732
YPO1011
Similar to Azospirillum irakense putative outer membrane salicin receptor salC TR:Q9LAE4 (EMBL:AF143227) (726 aa) fasta scores: E(): 0, 25.3% id in 730 aa, and to Escherichia coli probable TonB-dependent receptor YncD SW:YNCD_ECOLI (P76115) (700 aa) fasta scores: E(): 2.1e-15,22.9% id in 721 aa.
  
 
0.725
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
Server load: low (20%) [HD]