STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lacZBeta-galactosidase; Similar to Escherichia coli beta-galactosidase LacZ SW:BGAL_ECOLI (P00722) (1023 aa) fasta scores: E(): 0,62.5% id in 1046 aa, and to Enterobacter cloacae beta-galactosidase lacZ SW:BGAL_ENTCL (Q47077) (1028 aa) fasta scores: E(): 0, 60.4% id in 1046 aa; Belongs to the glycosyl hydrolase 2 family. (1060 aa)    
Predicted Functional Partners:
xylA
Xylose isomerase; Similar to Escherichia coli xylose isomerase XylA SW:XYLA_ECOLI (P00944) (440 aa) fasta scores: E(): 0, 85.4% id in 438 aa, and to Klebsiella pneumoniae xylose isomerase XylA SW:XYLA_KLEPN (P29442) (440 aa) fasta scores: E(): 0,84.2% id in 438 aa.
    
 0.949
glk
Glucokinase; Similar to Escherichia coli glucokinase Glk SW:HXKG_ECOLI (P46880) (321 aa) fasta scores: E(): 0, 79.4% id in 321 aa, and to Neisseria meningitidis (serogroup A) glucokinase Glk TR:Q9JQX3 (EMBL:AL162756) (328 aa) fasta scores: E(): 0, 46.6% id in 313 aa; Belongs to the bacterial glucokinase family.
   
 
 0.938
rafA
Alpha-galactosidase; Similar to Escherichia coli alpha-galactosidase RafA SW:RAFA_ECOLI (P16551) (708 aa) fasta scores: E(): 0, 57.9% id in 705 aa, and to Bacillus stearothermophilus alpha-galactosidase AgaN TR:Q9X624 (EMBL:AF130985) (729 aa) fasta scores: E(): 0, 31.4% id in 710 aa.
 
 
 0.897
galA
Aldose 1-epimerase (pseudogene); Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
 
 
 0.891
irp1
Previously sequenced as Yersinia pestis yersiniabactin biosynthetic protein Irp1 TR:Q9Z373 (EMBL:AL031866) (3163 aa) fasta scores: E(): 0, 100.0% id in 3163 aa. Similar to Yersinia enterocolitica HMWP1 protein Irp1 TR:O54511 (EMBL:Y12527) (3161 aa) fasta scores: E(): 0, 97.9% id in 3163 aa.
  
 
 0.890
bgaB
Puative beta-galactosidase; Similar to Clostridium perfringens beta-galactosidase Pbg TR:Q59312 (EMBL:D49537) (676 aa) fasta scores: E(): 0, 51.4% id in 675 aa, and to Bacillus circulans beta-D-galactosidase BgaB TR:Q45093 (EMBL:L03425) (690 aa) fasta scores: E(): 0, 61.6% id in 685 aa.
 
 
 0.876
fpk
1-phosphofructokinase; Similar to Escherichia coli 1-phosphofructokinase FruK or Fpk SW:K1PF_ECOLI (P23539) (312 aa) fasta scores: E(): 0, 92.0% id in 312 aa, and to Haemophilus influenzae 1-phosphofructokinase FruK SW:K1PF_HAEIN (P44330) (313 aa) fasta scores: E(): 0, 55.4% id in 305 aa; Belongs to the carbohydrate kinase PfkB family.
   
    0.840
YPO3019
Similar to Escherichia coli hypothetical protein YhcH SW:YHCH_ECOLI (P45424) (154 aa) fasta scores: E(): 9.6e-22, 47.6% id in 143 aa, and to Haemophilus influenzae hypothetical protein HI0227 SW:YHCH_HAEIN (P44583) (155 aa) fasta scores: E(): 2.1e-21, 48.3% id in 151 aa.
  
 0.791
YPO2541
Similar to Escherichia coli hypothetical protein YiaL SW:YIAL_ECOLI (P37673) (155 aa) fasta scores: E(): 5.8e-12, 34.0% id in 141 aa, and to Escherichia coli protein Yjgk SW:YJGK_ECOLI (P39335) (150 aa) fasta scores: E(): 6.4e-11, 34.5% id in 142 aa.
   
 0.788
YPO3447
Conserved hypothetical protein; Similar to Escherichia coli protein YjgK SW:YJGK_ECOLI (P39335) (150 aa) fasta scores: E(): 0, 71.1% id in 149 aa, and to Vibrio cholerae hypothetical protein VC1555 TR:Q9KRT1 (EMBL:AE004233) (170 aa) fasta scores: E(): 1.8e-20, 43.3% id in 150 aa.
   
 0.788
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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