STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
flhCFlagellar biosynthesis regulatory protein (pseudogene); Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (194 aa)    
Predicted Functional Partners:
motB
Similar to Escherichia coli chemotaxis MotB protein SW:MOTB_ECOLI (P09349) (308 aa) fasta scores: E(): 0, 68.8% id in 311 aa, and to Salmonella typhimurium chemotaxis MotB protein SW:MOTB_SALTY (P55892) (309 aa) fasta scores: E(): 0, 67.9% id in 312 aa. Note that this CDS is 119 aa longer,at the C-terminal end, than the MotB protein.
 
  
 0.944
motA-2
Similar to Escherichia coli chemotaxis MotA protein SW:MOTA_ECOLI (P09348) (295 aa) fasta scores: E(): 0, 81.0% id in 295 aa, and to Salmonella typhimurium chemotaxis MotA protein SW:MOTA_SALTY (P55891) (295 aa) fasta scores: E(): 0, 82.0% id in 295 aa.
 
    0.934
lafU
Similar to Escherichia coli chemotaxis protein MotB protein SW:MOTB_ECOLI (P09349) (308 aa) fasta scores: E(): 1.1e-23, 32.6% id in 310 aa, and to Vibrio parahaemolyticus chemotaxis protein LafU SW:LAFU_VIBPA (Q03478) (330 aa) fasta scores: E(): 0, 40.1% id in 297 aa.
  
  
 0.861
cheA
Chemotaxis protein CheA; Similar to Escherichia coli chemotaxis regulatory protein CheA SW:CHEA_ECOLI (P07363) (654 aa) fasta scores: E(): 0, 69.8% id in 716 aa, and to Salmonella typhimurium chemotaxis protein CheA SW:CHEA_SALTY (P09384) (671 aa) fasta scores: E(): 0, 72.2% id in 716 aa. This CDS contains internal insertions relative to that of E.coli and S. typhimurium.
  
  
 0.827
cheW
Chemotaxis protein CheW; Similar to Escherichia coli chemotaxis regulatory protein CheW SW:CHEW_ECOLI (P07365) (167 aa) fasta scores: E(): 0, 84.0% id in 163 aa, and to Salmonella typhimurium chemotaxis protein CheW SW:CHEW_SALTY (P06110) (167 aa) fasta scores: E(): 0, 84.4% id in 160 aa.
  
  
 0.793
cheC1
Flagellar protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
   
 0.792
flgA-2
Flagella basal body P-ring formation protein FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.
  
  
 0.791
flaO
Flagellar protein FliJ; Flagellar protein that affects chemotactic events. Belongs to the FliJ family.
  
   
 0.776
motA
Putative flagellar motor transmembrane channel protein; Similar to Escherichia coli chemotaxis protein MotA SW:MOTA_ECOLI (P09348) (295 aa) fasta scores: E(): 0, 37.9% id in 277 aa, and to Vibrio parahaemolyticus chemotaxis protein LafT SW:LAFT_VIBPA (Q03477) (285 aa) fasta scores: E(): 0, 56.4% id in 280 aa.
  
    0.747
flgM
Negative regulator of flagellin synthesis; Probable anti-sigma-28 factor. Similar to Yersinia enterocolitica negative regulator of flagellin synthesis FlgM SW:FLGM_YEREN (Q57401) (99 aa) fasta scores: E(): 5.7e-28, 87.6% id in 97 aa, and to Salmonella typhimurium negative regulator of flagellin synthesis FlgM or FlgR or MviS SW:FLGM_SALTY (P26477) (97 aa) fasta scores: E(): 1.5e-15, 59.2% id in 98 aa.
  
  
 0.736
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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